Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14046277 | 1.00 | KMT2A (0.57) | KMT2AALDH1A1MAPTOPRM1OPRL1 | |
| SCHEMBL14046170 | 1.00 | KMT2A (0.57) | KMT2AALDH1A1MAPTOPRM1OPRL1 | |
| SCHEMBL14046294 | 0.85 | KMT2A (0.54) | KMT2AALDH1A1MAPTOPRM1OPRL1 | |
| SCHEMBL14046309 | 0.85 | SLC6A3 (0.59) | KMT2AALDH1A1MAPTOPRM1LMNA | |
| SCHEMBL14046321 | 0.85 | KMT2A (0.54) | KMT2AALDH1A1MAPTOPRM1OPRL1 | |
| SCHEMBL14046325 | 0.85 | KMT2A (0.54) | KMT2AALDH1A1MAPTOPRM1OPRL1 | |
| SCHEMBL14046295 | 0.85 | SLC6A3 (0.59) | KMT2AALDH1A1MAPTOPRM1LMNA | |
| SCHEMBL4612537 | 0.81 | OPRD1 (0.48) | KMT2AALDH1A1MAPTOPRM1OPRL1 | |
| SCHEMBL14046322 | 0.80 | OPRM1 (0.64) | KMT2AALDH1A1MAPTOPRM1OPRL1 | |
| SCHEMBL14046169 | 0.80 | OPRM1 (0.64) | KMT2AALDH1A1MAPTOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269233-A1 | Piperidinoyl-Pyrrolidine and Piperidinoyl-Piperidine Compounds | ANDREWS MARK DAVID | 2008-10-30 | — | — | US | disclosed |
| US-20080234280-A1 | Use of Mc4 Receptor Agonist Compounds | MCMURRAY GORDON | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269233-A1 | Piperidinoyl-Pyrrolidine and Piperidinoyl-Piperidine Compounds | GPR4, GPR119, PRLHR | KMT2A 3354/4885ALDH1A1 590/4885MAPT 2380/4885 |
| US-20080234280-A1 | Use of Mc4 Receptor Agonist Compounds | MC4R, MC5R, GPR4 | KMT2A 3266/4885ALDH1A1 2792/4885MAPT 3206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.