Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14047605 | 0.81 | SCD (0.47) | SCDCYP3A4CYP2C9CYP2C19NAMPT | |
| SCHEMBL14047402 | 0.78 | SCD (0.62) | SCD | |
| SCHEMBL14162314 | 0.76 | SCD (0.47) | SCDCYP3A4CYP2C9CYP2C19NAMPT | |
| SCHEMBL244543 | 0.75 | SCD (0.76) | SCD | |
| SCHEMBL13541755 | 0.68 | P2RX7 (0.44) | NAMPTMAPTP2RX7 | |
| SCHEMBL13393741 | 0.68 | SCD (0.49) | SCDALDH1A1 | |
| SCHEMBL14162614 | 0.67 | ALDH1A1 (0.39) | CYP3A4CYP2C9CYP2C19NAMPTMAPT | |
| SCHEMBL14047532 | 0.67 | HDAC1 (0.44) | SCDKMT2AP2RX7 | |
| SCHEMBL14047577 | 0.67 | KMT2A (0.43) | SCDCYP3A4CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL14162281 | 0.67 | SCD (0.45) | SCDCYP3A4CYP2C9CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008127349-A2 | HETEROCYCLIC COMPOUNDS SUITABLE FOR THE TREATMENT OF DISEASES RELATED TO ELEVATED LIPID LEVEL | NOVARTIS AG (CH) | 2008-10-23 | — | — | WO | disclosed |