Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | IAPP | P10997 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8583110 | 0.86 | ALDH1A1 (0.60) | ALDH1A1CYP4F2CYP4A11NPC1RAB9A | |
| SCHEMBL14027395 | 0.86 | CYP4F2 (0.44) | ALDH1A1CYP4F2CYP4A11NPC1RAB9A | |
| SCHEMBL15093745 | 0.84 | KEAP1 (0.57) | ALDH1A1SLC6A3SMN1; SMN2FOLH1PPARG | |
| SCHEMBL1405098 | 0.84 | ALDH1A1 (0.63) | ALDH1A1RAB9ATP53SMN1; SMN2FOLH1 | |
| SCHEMBL18768957 | 0.83 | ALDH1A1 (0.72) | ALDH1A1CYP4F2CYP4A11NPC1RAB9A | |
| SCHEMBL1405064 | 0.83 | ALDH1A1 (0.56) | ALDH1A1CYP4F2CYP4A11NPC1RAB9A | |
| SCHEMBL3892580 | 0.82 | KAT6A (0.50) | ALDH1A1CYP4F2CYP4A11KDM4ETP53 | |
| SCHEMBL11138073 | 0.81 | ALDH1A1 (0.65) | ALDH1A1CYP4F2CYP4A11KDM4ELMNA | |
| SCHEMBL5207992 | 0.80 | CYP4F2 (0.45) | ALDH1A1CYP4F2CYP4A11TSHRFOLH1 | |
| SCHEMBL1405200 | 0.80 | SLC7A5 (0.58) | ALDH1A1CYP4F2CYP4A11NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079747-B1 | HETEROCYCLIC COMPOUNDS USEFUL AS ANABOLIC AGENTS FOR LIVESTOCK ANIMALS | PFIZER LTD (GB) | 2011-03-09 | — | — | EP | disclosed |
| US-20080161288-A1 | COMPOUNDS | PFIZER INC. | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161288-A1 | COMPOUNDS | ADRB2, ADRB1, ADRA2C | ALDH1A1 295/4885CYP4F2 63/4885CYP4A11 169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.