Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2675182 | 0.81 | HDAC1 (0.51) | MEN1ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL14049832 | 0.79 | NOS3 (0.54) | MEN1ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL11183187 | 0.77 | ALDH1A1 (0.68) | MEN1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL14049710 | 0.76 | NOS3 (0.57) | MEN1ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL12101222 | 0.75 | ALDH1A1 (0.58) | MEN1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL14049726 | 0.72 | CASP3 (0.46) | MEN1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL8212798 | 0.70 | TAAR1 (0.69) | HDAC1HDAC6HDAC8HDAC3HDAC4 | |
| SCHEMBL12156914 | 0.70 | ALOX15 (0.43) | MEN1ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL6808175 | 0.69 | MEN1 (0.44) | MEN1ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL5638347 | 0.68 | ALDH1A1 (0.64) | MEN1ALDH1A1KMT2AGAACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008116308-A1 | QUINOLONE AND TETRAHYDROQUINOLINE AND RELATED COMPOUNDS HAVING NOS INHIBITORY ACTIVITY | NEURAXON, INC. (CA) | 2008-10-02 | — | — | WO | disclosed |