Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | P4HB | P07237 | 3/20 | 0.62 |
| ▸ | TTR | P02766 | 5/20 | 0.60 |
| ▸ | UNG | P13051 | 1/20 | 0.59 |
| ▸ | FBP1 | P09467 | 1/20 | 0.57 |
| ▸ | IAPP | P10997 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1405148 | 1.00 | GLA (0.63) | GLATDP1P4HBTTRUNG | |
| SCHEMBL69236 | 0.85 | P4HB (0.66) | GLATDP1P4HBTTRUNG | |
| SCHEMBL69237 | 0.85 | P4HB (0.66) | GLATDP1P4HBTTRUNG | |
| SCHEMBL9075299 | 0.85 | TTR (0.79) | P4HBTTRUNGFBP1 | |
| SCHEMBL14441060 | 0.85 | GLA (0.72) | GLATDP1IAPPPTGS1HDAC3 | |
| SCHEMBL8899992 | 0.85 | TTR (0.79) | P4HBTTRUNGFBP1 | |
| SCHEMBL808972 | 0.85 | TTR (0.79) | P4HBTTRUNGFBP1 | |
| SCHEMBL808971 | 0.85 | TTR (0.79) | P4HBTTRUNGFBP1 | |
| SCHEMBL6170785 | 0.84 | GLA (0.56) | GLATDP1P4HBIAPPPTGS1 | |
| SCHEMBL6170786 | 0.84 | GLA (0.56) | GLATDP1P4HBIAPPPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079747-B1 | HETEROCYCLIC COMPOUNDS USEFUL AS ANABOLIC AGENTS FOR LIVESTOCK ANIMALS | PFIZER LTD (GB) | 2011-03-09 | — | — | EP | disclosed |
| CN-101535315-A | Heterocyclic compounds useful as anabolic agents for livestock animals | PFIZER LTD (GB) | 2009-09-16 | — | — | CN | disclosed |
| US-20080161288-A1 | COMPOUNDS | PFIZER INC. | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161288-A1 | COMPOUNDS | ADRB2, ADRB1, ADRA2C | GLA 1399/4885TDP1 4187/4885P4HB 2888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.