SCHEMBL1405340

SCHEMBL1405340

CC1=CCN2CCCCC2=C1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9026276 0.72 ALDH1A1 (0.32) MAPTALDH1A1
SCHEMBL8328693 0.65 MAPT (0.33) MAPTALDH1A1
SCHEMBL13308751 0.63 ALDH1A1 (0.36) MAPTALDH1A1
SCHEMBL368150 0.63 MAPT (0.37) MAPTALDH1A1HPGD
SCHEMBL497034 0.63 MAPT (0.37) MAPTALDH1A1HPGD
SCHEMBL18932504 0.63
SCHEMBL1405516 0.63 ACHE (0.30)
Hydrochloric Acid SCHEMBL3904361 0.61
SCHEMBL5130701 0.61 USP2 (0.32) HPGD
SCHEMBL23661069 0.61 ALDH1A1 (0.35) MAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2004713-B1 LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES CARESTREAM HEALTH INC (US) 2011-03-09 EP disclosed
EP-2188634-A1 FLUORESCENCE RESONANCE ENERGY TRANSFER DETECTION WITH NANOPARTICLES Carestream Health, Inc. (US) 2010-05-26 EP disclosed
WO-2010016858-A2 MOLECULAR IMAGING PROBES CARESTREAM HEALTH, INC. (US) 2010-02-11 WO disclosed
EP-2148701-A2 IMAGING CONTRAST AGENTS USING NANOPARTICLES Carestream Health, Inc. (US) 2010-02-03 EP disclosed
WO-2009032236-A1 FLUORESCENCE RESONANCE ENERGY TRANSFER DETECTION WITH NANOPARTICLES CARESTREAM HEALTH, INC. (US) 2009-03-12 WO disclosed
EP-2004713-A2 LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES Carestream Health, Inc. (US) 2008-12-24 EP disclosed
WO-2008140475-A2 IMAGING CONTRAST AGENTS USING NANOPARTICLES CARESTREAM HEALTH, INC. (US) 2008-11-20 WO disclosed
WO-2007120579-A2 LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES CARESTREAM HEALTH, INC. (US) 2007-10-25 WO disclosed
US-6460417-B1 Formability testing of small-size coatings and materials GENERAL ELECTRIC COMPANY 2002-10-08 US disclosed