Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23709489 | 0.77 | ALDH1A1 (0.34) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL14507095 | 0.69 | ALDH1A1 (0.38) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL15432005 | 0.68 | MAPT (0.61) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL18071053 | 0.68 | ALDH1A1 (0.36) | ALDH1A1MAPTGAAKMT2AHRH4 | |
| SCHEMBL29980540 | 0.67 | ADRA2C (0.34) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL29744932 | 0.64 | DRD2 (0.36) | ALDH1A1MAPTGAAKMT2AHRH4 | |
| SCHEMBL18639230 | 0.64 | ADRA2C (0.32) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL13308753 | 0.64 | ADRA2C (0.35) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL12785415 | 0.63 | ACHE (0.47) | HRH4 | |
| SCHEMBL1405340 | 0.63 | MAPT (0.35) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152407-A1 | NOVEL COMPOUNDS | LOCTITE (R&D) LIMITED (IE) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152407-A1 | NOVEL COMPOUNDS | KDM5B, KDM5C, KDM7A | ALDH1A1 241/4885MAPT 2836/4885GAA 698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.