Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Anthraquinone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CDC25B | P30305 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 2/20 | 0.44 |
| ▸ | TDP2 | O95551 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anthraquinone SCHEMBL1405498 | 0.92 | KMT2A (0.48) | MEN1KMT2ACDC25BMAPTMAPK1 | |
| Anthraquinone SCHEMBL6852507 | 0.91 | MEN1 (0.63) | MEN1KMT2ACDC25BMAPTMAPK1 | |
| Sulfuric Acid SCHEMBL1777697 | 0.89 | HTR6 (0.39) | MEN1KMT2AMAPTSMN1; SMN2KDM4E | |
| Anthraquinone SCHEMBL1405501 | 0.87 | MEN1 (0.52) | MEN1KMT2ACDC25BMAPTMAPK1 | |
| SCHEMBL3872550 | 0.81 | ALDH1A1 (0.50) | MAPTMAPK1SMN1; SMN2LMNATHRB | |
| Anthraquinone SCHEMBL5082838 | 0.81 | MEN1 (0.71) | MEN1KMT2ACDC25BMAPTMAPK1 | |
| SCHEMBL11393462 | 0.79 | FAAH (0.39) | KMT2AMAPTSMN1; SMN2KDM4ERAB9A | |
| Sulfuric Acid SCHEMBL1062108 | 0.79 | TSHR (0.44) | MEN1KMT2AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL1628635 | 0.79 | KEAP1 (0.39) | NPSR1 | |
| SCHEMBL454457 | 0.76 | HTR6 (0.44) | MEN1KMT2AHTTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8669040-B2 | Method of manufacturing relief printing plate and printing plate precursor for laser engraving | FUJIFILM CORPORATION (JP) | 2014-03-11 | — | — | US | disclosed |
| EP-2082874-B1 | Method of manufacturing relief printing plate | FUJIFILM CORP (JP) | 2011-03-09 | — | — | EP | disclosed |
| US-20090191481-A1 | Method of manufacturing relief printing plate and printing plate precursor for laser engraving | FUJIFILM CORPORATION (JP) | 2009-07-30 | — | — | US | disclosed |
| EP-2082874-A1 | Method of manufacturing relief printing plate and printing plate precursor for laser engraving | Fujifilm Corporation (JP) | 2009-07-29 | — | — | EP | disclosed |