SCHEMBL1628635

SCHEMBL1628635

CS(=O)(=O)[O-].c1ccc([I+]c2ccccc2)cc1

nearest known ligand 0.39

Known targets — ChEMBL curated mechanism

ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.39
PTGS2 P35354 7/20 0.39
CA12 O43570 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HTR6 P50406 1/20 0.36
PSIP1 O75475 1/20 0.36
ACHE P22303 1/20 0.34
MMP2 P08253 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL1777697 0.90 HTR6 (0.39) CA12CA2CA9L3MBTL1HTR6
SCHEMBL4452953 0.86 PSIP1 (0.43) CA12CA2CA9L3MBTL1PSIP1
SCHEMBL11393462 0.85 FAAH (0.39) CA12CA2CA9L3MBTL1HTR6
Sulfuric Acid SCHEMBL1062108 0.85 TSHR (0.44) CA12CA2CA9HTR6MMP2
SCHEMBL1718014 0.85 KEAP1 (0.44) KEAP1CA12CA2MMP2NPSR1
SCHEMBL7574610 0.84 ALDH1A1 (0.47) KEAP1PTGS2L3MBTL1
SCHEMBL454457 0.81 HTR6 (0.44) KEAP1CA12CA2CA9L3MBTL1
SCHEMBL978653 0.79 TSHR (0.39) CA12CA2CA9HTR6MMP2
Trifluoromethanesulfonic Acid SCHEMBL36177 0.79 GPR3 (0.50) CA2CA9ACHE
Anthraquinone SCHEMBL1405500 0.79 MEN1 (0.52) NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111484529-A Method for synthesizing tenofovir monophenyl ester 奥锐特药业股份有限公司 2020-08-04 CN claimed
US-6566036-B2 Comprising polyhydroxystyrene protected by 1-ethoxyethanol, photosensitive acid generator, solvent and polystyrene filler; dimensional and shape control of semiconductors; responsive to design rule of <0.15mu m; miniaturization NEC ELECTRONICS CORPORATION (JP) 2003-05-20 US claimed
US-20010009749-A1 Chemically amplified resist NEC CORPORATION 2001-07-26 US claimed
US-6200480-B1 CONTACTING IMPURE SOLUTION OF PHOTOACID GENERATING COMPOUND CONTAINING TRACE AMOUNTS OF ACIDIC IMPURITIES WITH ANIONIC ION EXCHANGE RESIN CONTAINING PENDENT POLYAMINE FUNCTIONAL GROUPS FOR SUFFICIENT AMOUNT OF TIME TO REMOVE SAID IMPURITIES ARCH SPECIALTY CHEMICALS, INC. 2001-03-13 US claimed
EP-1054715-A1 METHOD OF PURIFYING PHOTOACID GENERATORS FOR USE IN PHOTORESIST COMPOSITIONS Olin Microelectronic Chemicals, Inc. (US) 2000-11-29 EP claimed
WO-1999036151-A1 METHOD OF PURIFYING PHOTOACID GENERATORS FOR USE IN PHOTORESIST COMPOSITIONS OLIN MICROELECTRONIC CHEMICALS, INC. (US) 1999-07-22 WO claimed
US-20260117080-A1 METAL OXIDE PARTICLES HAVING CORE/SHELL STRUCTURE HAVING UNIFORM PARTICLE SIZE DISTRIBUTION, AND METHOD FOR PRODUCING SAME NISSAN CHEMICAL CORPORATION (JP) 2026-04-30 US disclosed
US-12606711-B2 Conductive stannic oxide particle-containing organic solvent-dispersed sol and method of production thereof NISSAN CHEMICAL CORPORATION (JP) 2026-04-21 US disclosed
US-20250256980-A1 METAL OXIDE PARTICLE HAVING CORE-SHELL STRUCTURE AND METHOD FOR PRODUCING SAME NISSAN CHEMICAL CORPORATION (JP) 2025-08-14 US disclosed
US-12359039-B2 Metal oxide particle-containing composition with reduced occurrence of volatile aldehydes NISSAN CHEMICAL CORPORATION (JP) 2025-07-15 US disclosed
WO-2025127152-A1 METAL OXIDE PARTICLES HAVING IMPROVED HYDROPHOBICITY, HIGHLY CONCENTRATED METAL OXIDE SOL, AND METHODS FOR PRODUCING SAME 日産化学株式会社 2025-06-19 WO disclosed
CN-119894824-A Hollow silica sol containing 1-valent alkali metal ion and method for producing same 日产化学株式会社 2025-04-25 CN disclosed
WO-2025084429-A1 SILICA PARTICLES FOR COATING COMPOSITION AND LAMINATED SUBSTRATE 日産化学株式会社 2025-04-24 WO disclosed
EP-1193553-A2 Exposure method, exposure apparatus, x-ray mask, semiconductor device and microstructure MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 2002-04-03 EP disclosed
US-20010009749-A1 Chemically amplified resist NEC CORPORATION 2001-07-26 US disclosed
US-6200480-B1 CONTACTING IMPURE SOLUTION OF PHOTOACID GENERATING COMPOUND CONTAINING TRACE AMOUNTS OF ACIDIC IMPURITIES WITH ANIONIC ION EXCHANGE RESIN CONTAINING PENDENT POLYAMINE FUNCTIONAL GROUPS FOR SUFFICIENT AMOUNT OF TIME TO REMOVE SAID IMPURITIES ARCH SPECIALTY CHEMICALS, INC. 2001-03-13 US disclosed
EP-1054715-A1 METHOD OF PURIFYING PHOTOACID GENERATORS FOR USE IN PHOTORESIST COMPOSITIONS Olin Microelectronic Chemicals, Inc. (US) 2000-11-29 EP disclosed
US-6080833-A BIS(HYDROXYALKOXYLATED) 1,1'-SPIROBIINDAN POLYCARBONATES AND POLYESTERS POLYMERS AND CURABLE COMPOUNDS SUCH AS BIS(ACRYLATED ALKOXY)SPIROBIINDANS; ALSO POLYAMIDES AND POLYIMIDES CONTAINING SPIROBIINDAN GROUPS MITSUI CHEMICALS, INC. (JP) 2000-06-27 US disclosed
WO-1999036151-A1 METHOD OF PURIFYING PHOTOACID GENERATORS FOR USE IN PHOTORESIST COMPOSITIONS OLIN MICROELECTRONIC CHEMICALS, INC. (US) 1999-07-22 WO disclosed
EP-0822545-A2 Optical component and spirobiindan polymer therefor MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1998-02-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260117080-A1 METAL OXIDE PARTICLES HAVING CORE/SHELL STRUCTURE HAVING UNIFORM PARTICLE SIZE DISTRIBUTION, AND METHOD FOR PRODUCING SAME CD63, SLC39A3, ZRANB2 KEAP1 4149/4885PTGS2 3709/4885CA12 988/4885
US-12606711-B2 Conductive stannic oxide particle-containing organic solvent-dispersed sol and method of production thereof SCO2, SOD1, SPOP KEAP1 4768/4885PTGS2 3940/4885CA12 889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.