SCHEMBL1405708

SCHEMBL1405708

O=C(CCl)c1ccc(O)c(C(=O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.53
CA2 P00918 3/20 0.53
PTGS2 P35354 3/20 0.52
CA12 O43570 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA14 Q9ULX7 2/20 0.52
ALOX5 P09917 1/20 0.52
KLKB1 P03952 1/20 0.52
CTSB P07858 1/20 0.52
MMP9 P14780 1/20 0.52
DNMT1 P26358 1/20 0.52
DNMT3B Q9UBC3 1/20 0.52
DNMT3L Q9UJW3 1/20 0.52
DNMT3A Q9Y6K1 1/20 0.52
ALDH1A1 P00352 3/20 0.48
HIF1A Q16665 3/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
KDM4E B2RXH2 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6065043 0.98 CA1 (0.52) CA1CA2PTGS2CA12CA7
SCHEMBL6064903 0.98 CA1 (0.52) CA1CA2PTGS2CA12CA7
SCHEMBL6065037 0.98 CA1 (0.52) CA1CA2PTGS2CA12CA7
SCHEMBL28009854 0.84 GSK3B (0.46) ALDH1A1HIF1AMEN1KMT2AKDM4E
SCHEMBL6065040 0.82 ALDH1A1 (0.44) CA1CA2ALDH1A1HIF1AMEN1
SCHEMBL6064902 0.82 GSK3B (0.44) CA1CA2ALDH1A1HIF1AMEN1
SCHEMBL1576999 0.81 CSNK2A1 (0.53) CA1CA2PTGS2CA12CA7
SCHEMBL3947199 0.81 PTPN1 (0.52) CA1CA2PTGS2CA12CA7
SCHEMBL11447833 0.81 CA1 (0.52) CA1CA2PTGS2CA12CA7
SCHEMBL1360224 0.81 KDM4E (0.53) CA1CA2PTGS2CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1446376-B1 COMPOSITIONS BASED ON CUPRIC SALTS, CUPRIC SALTS AND THEIR USE FOR CONTROLLING PHYTOPATHOGENS ISAGRO SPA (IT) 2011-03-09 EP claimed
CN-108842932-B High-adhesion polyolefin anti-adhesion film and preparation method thereof 江苏优珀斯材料科技有限公司 2021-03-19 CN disclosed
CN-109021858-B Weather-resistant release film and preparation method thereof 江苏优珀斯材料科技有限公司 2021-01-01 CN disclosed
US-8703750-B2 Mixtures and methods for the induction of resistance in plants ISAGRO S.P.A. (IT) 2014-04-22 US disclosed
US-8637058-B2 Compositions based on cupric salts, cupric salts and their use for controlling phytopathogens ISAGRO S.P.A. (IT) 2014-01-28 US disclosed
EP-1720408-B1 MIXTURES AND METHODS FOR THE INDUCTION OF RESISTANCE IN PLANTS ISAGRO SPA (IT) 2012-07-04 EP disclosed
CN-1925748-B Mixtures and methods for inducing resistance in plants ISAGRO SPA 2011-08-10 CN disclosed
EP-1446376-B1 COMPOSITIONS BASED ON CUPRIC SALTS, CUPRIC SALTS AND THEIR USE FOR CONTROLLING PHYTOPATHOGENS ISAGRO SPA (IT) 2011-03-09 EP disclosed
US-20100317519-A1 Mixtures and methods for the induction of resistance in plants ISAGRO S.P.A. (IT) 2010-12-16 US disclosed
US-20070173459-A1 Mixtures and methods for the induction of resistance in plants ISAGRO S.P.A. (IT) 2007-07-26 US disclosed
CN-1925748-A Mixtures and methods for inducing resistance in plants ISAGRO SPA (IT) 2007-03-07 CN disclosed
EP-1720408-A1 MIXTURES AND METHODS FOR THE INDUCTION OF RESISTANCE IN PLANTS ISAGRO S.p.A. (IT) 2006-11-15 EP disclosed
US-20050256091-A1 Compositions based on cupric salts cupric salts and their use for controlling phytopathogens ISAGRO S.P.A. (IT) 2005-11-17 US disclosed
WO-2005094580-A1 MIXTURES AND METHODS FOR THE INDUCTION OF RESISTANCE IN PLANTS ISAGRO S.P.A. (IT) 2005-10-13 WO disclosed
EP-1446376-A1 COMPOSITIONS BASED ON CUPRIC SALTS, CUPRIC SALTS AND THEIR USE FOR CONTROLLING PHYTOPATHOGENS ISAGRO S.p.A. (IT) 2004-08-18 EP disclosed
WO-2003043971-A1 COMPOSITIONS BASED ON CUPRIC SALTS, CUPRIC SALTS AND THEIR USE FOR CONTROLLING PHYTOPATHOGENS ISAGRO S.P.A. (IT) 2003-05-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050256091-A1 Compositions based on cupric salts cupric salts and their use for controlling phytopathogens ME1, COPS5, COPS2 CA1 94/4885CA2 37/4885PTGS2 2267/4885
US-20070173459-A1 Mixtures and methods for the induction of resistance in plants SLC11A2, MYD88, ME2 CA1 2906/4885CA2 2786/4885PTGS2 51/4885
US-20100317519-A1 Mixtures and methods for the induction of resistance in plants SLC11A2, MYD88, ME2 CA1 2906/4885CA2 2786/4885PTGS2 51/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.