Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 5/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.38 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14163064 | 0.82 | HTT (0.42) | TSHRKDM4EHTTMAPTSMN1; SMN2 | |
| SCHEMBL8404656 | 0.79 | TSHR (0.41) | TSHRKDM4EHTTMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9811575 | 0.77 | ALDH1A1 (0.55) | TSHRKDM4EHTTMAPTPOLB | |
| SCHEMBL497608 | 0.76 | — | — | |
| SCHEMBL23951352 | 0.76 | ACHE (0.49) | GAAALDH1A1KMT2ACHRM2CHRM3 | |
| SCHEMBL9654472 | 0.76 | CCR5 (0.39) | TSHRMAPTSLC18A3ALDH1A1LMNA | |
| SCHEMBL10079150 | 0.76 | SLC6A2 (0.49) | TSHRKDM4EHTTMAPTPOLB | |
| SCHEMBL23108078 | 0.75 | MAPT (0.47) | TSHRKDM4EHTTMAPTPOLB | |
| Hydrochloric Acid SCHEMBL11286601 | 0.74 | — | — | |
| SCHEMBL31682629 | 0.73 | MAPT (0.42) | TSHRKDM4EHTTMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325910-B1 | ALIPHATIC NITROGENOUS FIVE-MEMBERED RING COMPOUNDS | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-09-17 | — | — | EP | disclosed |