Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 5/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | MAP1LC3B | Q9GZQ8 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD5 | P21918 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9654191 | 0.79 | CCR2 (0.42) | CCR5DRD2SLC18A3SLC6A4DRD3 | |
| SCHEMBL9655269 | 0.78 | CCR5 (0.46) | CCR5ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL9652034 | 0.77 | DRD2 (0.47) | ALDH1A1TSHRKMT2ADRD2SLC6A4 | |
| SCHEMBL8404656 | 0.76 | TSHR (0.41) | ALDH1A1LMNAMAPTTSHRKMT2A | |
| SCHEMBL14163064 | 0.76 | HTT (0.42) | ALDH1A1MAPTTSHRDRD2SLC6A4 | |
| SCHEMBL14067274 | 0.76 | TSHR (0.42) | CCR5ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL10079150 | 0.70 | SLC6A2 (0.49) | ALDH1A1MAPTTSHRKMT2ASLC6A4 | |
| Hydrochloric Acid SCHEMBL9811575 | 0.70 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPTTSHRKMT2A | |
| SCHEMBL9342501 | 0.69 | ALDH1A1 (0.45) | ALDH1A1MAPT | |
| SCHEMBL9094536 | 0.68 | SIGMAR1 (0.44) | DRD2HTR1ADRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502024-A1 | 4-HETEROARYL PIPERIDINE INTERMEDIATES AND THEIR PREPARATION. | NOVO NORDISK AS (DK) | 1992-09-09 | — | — | EP | claimed |
| WO-1991007398-A1 | 4-HETEROARYL PIPERIDINE INTERMEDIATES AND THEIR PREPARATION | NOVO NORDISK A/S (DK) | 1991-05-30 | — | — | WO | claimed |
| EP-0505465-A1 | PIPERIDINE COMPOUNDS AND A PHARMACEUTICAL COMPOSITION. | NOVO NORDISK AS (DK) | 1992-09-30 | — | — | EP | disclosed |
| EP-0502024-A1 | 4-HETEROARYL PIPERIDINE INTERMEDIATES AND THEIR PREPARATION. | NOVO NORDISK AS (DK) | 1992-09-09 | — | — | EP | disclosed |
| WO-1991009032-A1 | PIPERIDINE COMPOUNDS AND A PHARMACEUTICAL COMPOSITION | NOVO NORDISK A/S (DK) | 1991-06-27 | — | — | WO | disclosed |
| WO-1991007398-A1 | 4-HETEROARYL PIPERIDINE INTERMEDIATES AND THEIR PREPARATION | NOVO NORDISK A/S (DK) | 1991-05-30 | — | — | WO | disclosed |