Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | DRD3 | P35462 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28416949 | 0.98 | HTR6 (0.53) | HTR6DRD2DRD3ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL31084057 | 0.98 | HTR6 (0.53) | HTR6DRD2DRD3ALDH1A1HPGD | |
| SCHEMBL29868252 | 0.88 | HTR6 (0.51) | HTR6DRD2DRD3HTR2AHTR2C | |
| SCHEMBL8115507 | 0.86 | HTR6 (0.55) | HTR6DRD2DRD3HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL29868235 | 0.86 | HTR6 (0.50) | HTR6DRD2DRD3HTR2AHTR2C | |
| SCHEMBL3249580 | 0.86 | PNMT (0.62) | HTR6DRD2DRD3HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL4789165 | 0.85 | HTR6 (0.54) | HTR6DRD2DRD3HTR2AHTR2C | |
| SCHEMBL10360424 | 0.79 | HTR6 (0.66) | HTR6DRD2DRD3ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7014506 | 0.77 | HTR6 (0.64) | HTR6DRD2DRD3ALDH1A1LMNA | |
| SCHEMBL19407006 | 0.76 | DRD2 (0.42) | HTR6DRD2DRD3ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111018891-B | Substituted amino six-membered saturated heteroalicyclic as long acting DPP-IV inhibitors | 正大天晴药业集团股份有限公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-111018891-A | Substituted amino six-membered saturated heteroalicyclic as long acting DPP-IV inhibitors | 正大天晴药业集团股份有限公司 | 2020-04-17 | — | — | CN | disclosed |
| US-10155775-B2 | Substituted amino six-membered saturated heteroalicycles as long-acting DPP-IV inhibitors | CENTAURUS BIOPHARMA CO., LTD. (CN) | 2018-12-18 | — | — | US | disclosed |
| US-20180111950-A1 | SUBSTITUTED AMINO SIX-MEMBERED SATURATED HETEROALICYCLES AS LONG-ACTING DPP-IV INHIBITORS | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2018-04-26 | — | — | US | disclosed |
| US-20180111950-A1 | SUBSTITUTED AMINO SIX-MEMBERED SATURATED HETEROALICYCLES AS LONG-ACTING DPP-IV INHIBITORS | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2018-04-26 | — | — | US | disclosed |
| EP-3257857-A1 | SUBSTITUTED AMINO SIX-MEMBERED SATURATED HETEROCYCLIC FAT USED AS LONG-ACTING DPP-IV INHIBITOR | Centaurus BioPharma Co., Ltd. (CN) | 2017-12-20 | — | — | EP | disclosed |
| EP-3257857-A1 | SUBSTITUTED AMINO SIX-MEMBERED SATURATED HETEROCYCLIC FAT USED AS LONG-ACTING DPP-IV INHIBITOR | Centaurus BioPharma Co., Ltd. (CN) | 2017-12-20 | — | — | EP | disclosed |
| WO-2016127916-A1 | SUBSTITUTED AMINO SIX-MEMBERED SATURATED HETEROCYCLIC FAT USED AS LONG-ACTING DPP-IV INHIBITOR | 北京赛林泰医药技术有限公司 | 2016-08-18 | — | — | WO | disclosed |
| EP-1325910-B1 | ALIPHATIC NITROGENOUS FIVE-MEMBERED RING COMPOUNDS | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180111950-A1 | SUBSTITUTED AMINO SIX-MEMBERED SATURATED HETEROALICYCLES AS LONG-ACTING DPP-IV INHIBITORS | DPP4, DPP7, DPP9 | HTR6 26/4885DRD2 1156/4885DRD3 1933/4885 |
| US-10155775-B2 | Substituted amino six-membered saturated heteroalicycles as long-acting DPP-IV inhibitors | DPP4, DPP7, DPP9 | HTR6 26/4885DRD2 1156/4885DRD3 1933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.