Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15264231 | 0.75 | GFPT1 (0.56) | HCAR2NFE2L2KEAP1GFPT1ALDH1A1 | |
| SCHEMBL15264235 | 0.75 | GFPT1 (0.56) | HCAR2NFE2L2KEAP1GFPT1ALDH1A1 | |
| SCHEMBL10337138 | 0.74 | TSHR (0.37) | ALDH1A1MAPTTDP1EGLN1ALOX15 | |
| Dimethyl Fumarate SCHEMBL28128958 | 0.74 | NFE2L2 (1.00) | HCAR2NFE2L2KEAP1GFPT1ALDH1A1 | |
| Dimethyl Fumarate SCHEMBL41836 | 0.74 | NFE2L2 (1.00) | HCAR2NFE2L2KEAP1GFPT1ALDH1A1 | |
| Dimethyl Fumarate SCHEMBL11668350 | 0.74 | NFE2L2 (1.00) | HCAR2NFE2L2KEAP1GFPT1ALDH1A1 | |
| Dimethyl Maleate SCHEMBL27720952 | 0.74 | NFE2L2 (1.00) | HCAR2NFE2L2KEAP1GFPT1ALDH1A1 | |
| Dimethyl Maleate SCHEMBL75864 | 0.74 | NFE2L2 (1.00) | HCAR2NFE2L2KEAP1GFPT1ALDH1A1 | |
| Dimethyl Fumarate SCHEMBL41835 | 0.74 | NFE2L2 (1.00) | HCAR2NFE2L2KEAP1GFPT1ALDH1A1 | |
| SCHEMBL19222532 | 0.73 | HCAR2 (0.52) | HCAR2NFE2L2KEAP1GFPT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080227847-A1 | Novel Salts of Fumaric Acid Monoalkylesters and Their Pharmaceutical Use | ADITECH PHARMA AB (SE) | 2008-09-18 | — | — | US | disclosed |
| US-20080227847-A1 | Novel Salts of Fumaric Acid Monoalkylesters and Their Pharmaceutical Use | ADITECH PHARMA AB (SE) | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227847-A1 | Novel Salts of Fumaric Acid Monoalkylesters and Their Pharmaceutical Use | FAH, SLC16A1, FH | HCAR2 42/4885NFE2L2 215/4885KEAP1 426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.