Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8257845 | 0.87 | CNR2 (0.38) | CNR2SCN9A | |
| SCHEMBL30465990 | 0.78 | ACHE (0.43) | PARP1ACHEDRD2 | |
| SCHEMBL7516624 | 0.78 | ACHE (0.43) | PARP1ACHEDRD2 | |
| SCHEMBL14070892 | 0.75 | CTNNB1 (0.40) | HTR1APARP1TRPV1 | |
| SCHEMBL27837686 | 0.73 | KDM4E (0.35) | — | |
| SCHEMBL5692114 | 0.73 | RXRB (0.42) | SSTR4 | |
| Bicarbonate SCHEMBL9415505 | 0.72 | CTNNB1 (0.44) | PARP1ACHE | |
| SCHEMBL2319086 | 0.72 | ALDH1A1 (0.36) | TRPV1CNR2SCN9A | |
| SCHEMBL7524518 | 0.72 | KDM4E (0.44) | HTR1APARP1SLC6A4DRD2 | |
| SCHEMBL7519010 | 0.72 | HTR1A (0.38) | HTR1ASLC6A4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013096226-A1 | TRPV1 ANTAGONISTS | ABBVIE INC. (US) | 2013-06-27 | — | — | WO | disclosed |
| US-7429411-B2 | Chroman compound, liquid crystal composition including the compound and liquid crystal display element including the liquid crystal composition | CHISSO PETROCHEMICAL CORPORATION (JP) | 2008-09-30 | — | — | US | disclosed |
| US-7429411-B2 | Chroman compound, liquid crystal composition including the compound and liquid crystal display element including the liquid crystal composition | CHISSO PETROCHEMICAL CORPORATION (JP) | 2008-09-30 | — | — | US | disclosed |