Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.70 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.70 |
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.60 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.58 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14073571 | 0.91 | ALDH1A1 (0.63) | CYP3A4CYP19A1CYP1A2RAB9ANPC1 | |
| SCHEMBL14073778 | 0.86 | CYP3A4 (0.61) | CYP3A4CYP19A1CYP1A2RAB9AALDH1A1 | |
| SCHEMBL30444601 | 0.86 | KMT2A (0.62) | CYP3A4CYP19A1CYP1A2RAB9ANPC1 | |
| SCHEMBL14073852 | 0.85 | CYP3A4 (0.61) | CYP3A4CYP19A1CYP1A2RAB9ANPC1 | |
| SCHEMBL22284858 | 0.85 | CYP3A4 (0.63) | CYP3A4CYP19A1CYP1A2RAB9ANPC1 | |
| SCHEMBL30444662 | 0.85 | CYP3A4 (0.63) | CYP3A4CYP19A1CYP1A2RAB9ANPC1 | |
| SCHEMBL29478290 | 0.83 | CYP3A4 (1.00) | CYP3A4CYP19A1CYP1A2RAB9ANPC1 | |
| SCHEMBL18770307 | 0.83 | CYP3A4 (1.00) | CYP3A4CYP19A1CYP1A2RAB9ANPC1 | |
| SCHEMBL14073845 | 0.83 | CYP3A4 (0.82) | CYP3A4CYP19A1CYP1A2ALDH1A1CYP2C9 | |
| SCHEMBL14073771 | 0.82 | CYP3A4 (0.60) | CYP3A4CYP19A1CYP1A2ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221093-A1 | Metalloprotease inhibitors containing a heterocyclic moiety | ALANTOS PHARMACEUTICALS HOLDING, INC. | 2008-09-11 | — | — | US | disclosed |
| US-20080221093-A1 | Metalloprotease inhibitors containing a heterocyclic moiety | ALANTOS PHARMACEUTICALS HOLDING, INC. | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221093-A1 | Metalloprotease inhibitors containing a heterocyclic moiety | MMP12, MMP13, MMP25 | CYP3A4 376/4885CYP19A1 651/4885CYP1A2 415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.