Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14073783 | 0.91 | CYP3A4 (0.70) | ALDH1A1RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL14073572 | 0.86 | KMT2A (0.63) | ALDH1A1RAB9ASMN1; SMN2KMT2ACYP1A2 | |
| SCHEMBL14073600 | 0.85 | KMT2A (0.59) | ALDH1A1KMT2ACYP1A2CYP3A4CYP19A1 | |
| SCHEMBL8192718 | 0.83 | ALDH1A1 (0.77) | ALDH1A1KMT2AMAPTPOLBTRPV1 | |
| SCHEMBL14073594 | 0.83 | CYP2C9 (0.69) | ALDH1A1KMT2ACYP1A2CYP3A4CYP19A1 | |
| SCHEMBL14073570 | 0.82 | MAPT (0.60) | ALDH1A1KMT2ACYP1A2CYP3A4CYP19A1 | |
| SCHEMBL14073604 | 0.82 | ROCK2 (0.60) | ALDH1A1KMT2ACYP1A2CYP3A4CYP19A1 | |
| SCHEMBL14073285 | 0.82 | HPGD (0.65) | ALDH1A1NPC1CYP1A2CYP3A4CYP19A1 | |
| SCHEMBL4264640 | 0.81 | ALDH1A1 (0.56) | ALDH1A1CYP1A2CYP3A4CYP19A1MAPT | |
| SCHEMBL23143601 | 0.81 | RAB9A (0.61) | ALDH1A1RAB9ANPC1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221093-A1 | Metalloprotease inhibitors containing a heterocyclic moiety | ALANTOS PHARMACEUTICALS HOLDING, INC. | 2008-09-11 | — | — | US | disclosed |
| US-20080221093-A1 | Metalloprotease inhibitors containing a heterocyclic moiety | ALANTOS PHARMACEUTICALS HOLDING, INC. | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221093-A1 | Metalloprotease inhibitors containing a heterocyclic moiety | MMP12, MMP13, MMP25 | ALDH1A1 714/4885RAB9A 2232/4885NPC1 2740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.