Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.60 |
| ▸ | NPC1 | O15118 | 11/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 8/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14073627 | 0.92 | NPC1 (0.60) | RAB9ANPC1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL14073935 | 0.83 | MAPT (0.64) | RAB9ANPC1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL14073931 | 0.81 | CYP3A4 (0.56) | RAB9ANPC1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL14073692 | 0.81 | ALDH1A1 (0.72) | RAB9ANPC1KMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL14073886 | 0.80 | CYP3A4 (0.55) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL14073936 | 0.80 | MAPT (0.56) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL14073830 | 0.79 | NPC1 (0.56) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL14073031 | 0.78 | ALDH1A1 (0.69) | RAB9ANPC1KMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL14073771 | 0.78 | CYP3A4 (0.60) | KMT2ACYP3A4CYP19A1CYP2C9POLB | |
| SCHEMBL14073377 | 0.78 | TSHR (0.63) | RAB9ANPC1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221093-A1 | Metalloprotease inhibitors containing a heterocyclic moiety | ALANTOS PHARMACEUTICALS HOLDING, INC. | 2008-09-11 | — | — | US | disclosed |
| US-20080221093-A1 | Metalloprotease inhibitors containing a heterocyclic moiety | ALANTOS PHARMACEUTICALS HOLDING, INC. | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221093-A1 | Metalloprotease inhibitors containing a heterocyclic moiety | MMP12, MMP13, MMP25 | RAB9A 2232/4885NPC1 2740/4885KMT2A 2900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.