Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.60 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.60 |
| ▸ | AXL | P30530 | 1/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.50 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30095652 | 0.84 | ADORA2A (0.54) | ADORA2AADORA2BAXLMKNK1MKNK2 | |
| SCHEMBL29494878 | 0.82 | ADORA2A (0.56) | ADORA2AADORA2BAXLMKNK1MKNK2 | |
| SCHEMBL14074693 | 0.81 | ADORA2A (0.56) | ADORA2AADORA2BAXLMKNK1MKNK2 | |
| SCHEMBL12590823 | 0.74 | ADORA2A (0.48) | ADORA2AADORA2BAXLMKNK1MKNK2 | |
| SCHEMBL28762328 | 0.72 | ADORA2A (0.47) | ADORA2AADORA2BAXLMKNK1MKNK2 | |
| SCHEMBL10650329 | 0.71 | ALDH1A1 (0.44) | ADORA2AADORA2BAXLMKNK1MKNK2 | |
| SCHEMBL6642089 | 0.71 | AXL (0.59) | ADORA2AADORA2BAXLMKNK1MKNK2 | |
| SCHEMBL424626 | 0.71 | AXL (0.59) | ADORA2AADORA2BAXLMKNK1MKNK2 | |
| Trifluoroacetic Acid SCHEMBL31745019 | 0.69 | ADORA2A (0.44) | ADORA2AADORA2BAXLMKNK1MKNK2 | |
| SCHEMBL13229696 | 0.69 | MEN1 (0.40) | ADORA2AADORA2BAXLMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221092-A1 | Heterobicyclic metalloprotease inhibitors | BLUHM HARALD | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221092-A1 | Heterobicyclic metalloprotease inhibitors | MMP13, MMP3, TIMP3 | ADORA2A 3168/4885ADORA2B 2346/4885AXL 4551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.