SCHEMBL140748

SCHEMBL140748

[C-]#[N+]/C(C#N)=C\c1ccc(N2CCCCC2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.63
ALDH1A1 P00352 7/20 0.63
SMN1; SMN2 Q16637 6/20 0.63
MEN1 O00255 6/20 0.63
KMT2A Q03164 6/20 0.63
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
LMNA P02545 3/20 0.50
MAPK1 P28482 2/20 0.50
CASP3 P42574 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
KDM4E B2RXH2 1/20 0.46
TRIM24 O15164 1/20 0.44
TRIM33 Q9UPN9 1/20 0.44
PTGS2 P35354 1/20 0.42
TNNI3 P19429 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL141719 1.00 MAPT (0.63) MAPTALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL12554054 0.87 MEN1 (0.67) MAPTALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL255365 0.80 MEN1 (0.97) MAPTALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL255364 0.80 MEN1 (0.97) MAPTALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL12445012 0.79 MEN1 (0.48) MAPTALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL14571074 0.78 ALDH1A1 (0.71) MAPTALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL32675887 0.78 MEN1 (1.00) MAPTALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL10046608 0.77 ALDH1A1 (0.69) MAPTALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL12445013 0.76 MEN1 (0.45) MAPTALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL16312152 0.75 ALDH1A1 (0.71) MAPTALDH1A1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9500932-B2 Fast-response photorefractive polymer element NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGY (JP) 2016-11-22 US disclosed
US-9436060-B2 Islands-in-sea type photorefractive polymer composite, and photorefractive device and optical device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-09-06 US disclosed
US-9164382-B2 Photorefractive composite, spatial light modulator, and hologram display device using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-10-20 US disclosed
US-9134550-B2 Photorefractive polymer composite, and photorefractive device and hologram display device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-09-15 US disclosed
US-20150227019-A1 FAST-RESPONSE PHOTOREFRACTIVE POLYMER ELEMENT NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGY (JP) 2015-08-13 US disclosed
US-9097970-B2 Photorefractive composite, spatial light modulator, and hologram display device using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-08-04 US disclosed
US-20140253997-A1 ISLANDS-IN-SEA TYPE PHOTOREFRACTIVE POLYMER COMPOSITE, AND PHOTOREFRACTIVE DEVICE AND OPTICAL DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2014-09-11 US disclosed
US-20140133000-A1 PHOTOREFRACTIVE POLYMER COMPOSITE, AND PHOTOREFRACTIVE DEVICE AND HOLOGRAM DISPLAY DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2014-05-15 US disclosed
US-20130163086-A1 SYSTEMS AND METHODS FOR IMPROVING THE PERFORMANCE OF A PHOTOREFRACTIVE DEVICE BY UTILIZING ELECTROLYTES NITTO DENKO CORPORATION (JP) 2013-06-27 US disclosed
US-20130148180-A1 PHOTOREFRACTIVE COMPOSITE, SPATIAL LIGHT MODULATOR, AND HOLOGRAM DISPLAY DEVICE USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-06-13 US disclosed
US-20130148181-A1 PHOTOREFRACTIVE COMPOSITE, SPATIAL LIGHT MODULATOR, AND HOLOGRAM DISPLAY DEVICE USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-06-13 US disclosed
US-8203780-B2 Systems and methods for improving the performance of a photorefractive device NITTO DENKO CORPORATION (JP) 2012-06-19 US disclosed
US-20120058418-A1 THREE-DIMENSIONAL HOLOGRAPHIC DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2012-03-08 US disclosed
US-7985356-B2 Non-linear optical device sensitive to green laser NITTO DENKO CORPORATION (JP) 2011-07-26 US disclosed
US-7736548-B2 Non-linear optical device with long grating persistency NITTO DENKO CORPORATION (JP) 2010-06-15 US disclosed
US-20100060975-A1 SYSTEMS AND METHODS FOR IMPROVING THE PERFORMANCE OF A PHOTOREFRACTIVE DEVICE NITTO DENKO CORPORATION (JP) 2010-03-11 US disclosed
US-20090092746-A1 PHOTOREFRACTIVE COMPOSITIONS WITH NANOPARTICLES NITTO DENKO CORPORATION (JP) 2009-04-09 US disclosed
US-20090052009-A1 NON-LINEAR OPTICAL DEVICE SENSITIVE TO GREEN LASER NITTO DENKO CORPORATION (JP) 2009-02-26 US disclosed
US-20080039603-A1 NON-LINEAR OPTICAL DEVICE WITH LONG GRATING PERSISTENCY NITTO DENKO CORPORATION (JP) 2008-02-14 US disclosed
US-7186781-B2 Fullerene-containing polymer, producing method thereof, and photorefractive composition NITTO DENKO CORPORATION (JP) 2007-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130148181-A1 PHOTOREFRACTIVE COMPOSITE, SPATIAL LIGHT MODULATOR, AND HOLOGRAM DISPLAY DEVICE USING THE SAME CRY1, HTR3D, GRK1 MAPT 3668/4885ALDH1A1 59/4885SMN1; SMN2 4524/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.