SCHEMBL255365

SCHEMBL255365

N#CC(C#N)=Cc1ccc(N2CCCCCC2)cc1

nearest known ligand 0.97

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 9/20 0.97
KMT2A Q03164 9/20 0.97
ALDH1A1 P00352 9/20 0.97
MAPT P10636 8/20 0.97
SMN1; SMN2 Q16637 5/20 0.97
LMNA P02545 5/20 0.59
KDM4E B2RXH2 3/20 0.59
NPSR1 Q6W5P4 2/20 0.59
POLB P06746 1/20 0.59
CRHBP P24387 1/20 0.57
HTT P42858 1/20 0.57
CRHR2 Q13324 1/20 0.57
TNNI3 P19429 1/20 0.57
TNNT2 P45379 1/20 0.57
TNNC1 P63316 1/20 0.57
NPC1 O15118 3/20 0.56
RAB9A P51151 3/20 0.56
MAPK1 P28482 1/20 0.56
CASP3 P42574 1/20 0.56
SENP8 Q96LD8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL255364 1.00 MEN1 (0.97) MEN1KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL32675887 0.98 MEN1 (1.00) MEN1KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL8724442 0.89 MEN1 (0.82) MEN1KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL1009547 0.85 KMT2A (1.00) MEN1KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL14571074 0.85 ALDH1A1 (0.71) MEN1KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL10046608 0.83 ALDH1A1 (0.69) MEN1KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL16312152 0.81 ALDH1A1 (0.71) MEN1KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL141719 0.80 MAPT (0.63) MEN1KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL15138675 0.80 ALDH1A1 (0.67) MEN1KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL140748 0.80 MAPT (0.63) MEN1KMT2AALDH1A1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9746622-B2 Optical coupling with a rewritable photorefractive polymer layer EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2017-08-29 US disclosed
US-9500932-B2 Fast-response photorefractive polymer element NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGY (JP) 2016-11-22 US disclosed
US-20160154192-A1 REWRITABLE PHOTOREFRACTIVE POLYMER LAYER FOR OPTICAL FIBER COUPLING CRESTLINE DIRECT FINANCE, L.P. 2016-06-02 US disclosed
WO-2015163896-A1 REWRITABLE PHOTOREFRACTIVE POLYMER LAYER FOR OPTICAL FIBER COUPLING EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2015-10-29 WO disclosed
US-20150227019-A1 FAST-RESPONSE PHOTOREFRACTIVE POLYMER ELEMENT NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGY (JP) 2015-08-13 US disclosed
WO-2013148892-A1 BENZYLIDENE DERIVATIVE CHROMOPHORES FOR PHOTOREFRACTIVE COMPOSITIONS NITTO DENKO CORPORATION (JP) 2013-10-03 WO disclosed
WO-2013148892-A1 BENZYLIDENE DERIVATIVE CHROMOPHORES FOR PHOTOREFRACTIVE COMPOSITIONS NITTO DENKO CORPORATION (JP) 2013-10-03 WO disclosed
EP-1578884-B1 POLYMER, PRODUCING METHOD THEREOF, AND PHOTOREFRACTIVE COMPOSITION NITTO DENKO CORP (JP) 2013-04-24 EP disclosed
EP-1578884-B1 POLYMER, PRODUCING METHOD THEREOF, AND PHOTOREFRACTIVE COMPOSITION NITTO DENKO CORP (JP) 2013-04-24 EP disclosed
WO-2013037404-A1 PHOTOREFRACTIVE COMPOSITE Westfälische Wilhelms Universität Münster (DE) 2013-03-21 WO disclosed
JP-2006018112-A ORGANIC PHOTOREFRACTIVE MATERIAL NITTO DENKO CORP 2006-01-19 JP disclosed
EP-1578884-A2 POLYMER, PRODUCING METHOD THEREOF, AND PHOTOREFRACTIVE COMPOSITION NITTO DENKO CORPORATION (JP) 2005-09-28 EP disclosed
US-20050157358-A1 Process for producing optical recording element NITTO DENKO CORPORATION 2005-07-21 US disclosed
US-20050051758-A1 Polysiloxane with pendant triphenylamine groups; photoconductive (charge transport) and non-linear optical ability; sensitizers, plasticizers NITTO DENKO CORPORATION (JP) 2005-03-10 US disclosed
US-20040265740-A1 Fullerene-containing polymer, producing method thereof, and photorefractive composition YAMAMOTO MICHIHARU (US) 2004-12-30 US disclosed
US-6809156-B2 ACRYLATE BASED POLYMERS HAVING CHARGE TRANSPORT AND NONLINEAR OPTICAL COMPONENTS; INJECTION OR EXTRUSION MOLDING WORKABILITY NITTO DENKO CORPORATION (JP) 2004-10-26 US disclosed
US-20040077794-A1 Fullerene-containing polymer, producing method thereof, and photorefractive composition NITTO DENKO CORPORATION (JP) 2004-04-22 US disclosed
US-6653421-B1 Addition copolymer with pendant carbazole and/or triphenylamine groups; photoconductive (charge transport) and non-linear optical ability; sensitizers, plasticizers NITTO DENKO CORPORATION (JP) 2003-11-25 US disclosed
WO-2003085065-A2 POLYMER, PRODUCING METHOD THEREOF, AND PHOTOREFRACTIVE COMPOSITION NITTO DENKO CORPORATION (JP) 2003-10-16 WO disclosed
US-6610809-B1 Charge transport and nonlinear optical ability; living radical polymerization, initiator, transition metal catalyst and a ligand reversibly forming a complex with the transition metal catalyst; acrylic ester monomer NITTO DENKO CORPORATION (JP) 2003-08-26 US disclosed