SCHEMBL255364

SCHEMBL255364

N#CC(C#N)=Cc1ccc(N2CCCCC2)cc1

nearest known ligand 0.97

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 9/20 0.97
KMT2A Q03164 9/20 0.97
ALDH1A1 P00352 9/20 0.97
MAPT P10636 8/20 0.97
SMN1; SMN2 Q16637 5/20 0.97
LMNA P02545 5/20 0.59
KDM4E B2RXH2 3/20 0.59
NPSR1 Q6W5P4 2/20 0.59
POLB P06746 1/20 0.59
CRHBP P24387 1/20 0.57
HTT P42858 1/20 0.57
CRHR2 Q13324 1/20 0.57
TNNI3 P19429 1/20 0.57
TNNT2 P45379 1/20 0.57
TNNC1 P63316 1/20 0.57
NPC1 O15118 3/20 0.56
RAB9A P51151 3/20 0.56
MAPK1 P28482 1/20 0.56
CASP3 P42574 1/20 0.56
SENP8 Q96LD8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL255365 1.00 MEN1 (0.97) MEN1KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL32675887 0.98 MEN1 (1.00) MEN1KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL8724442 0.89 MEN1 (0.82) MEN1KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL1009547 0.85 KMT2A (1.00) MEN1KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL14571074 0.85 ALDH1A1 (0.71) MEN1KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL10046608 0.83 ALDH1A1 (0.69) MEN1KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL16312152 0.81 ALDH1A1 (0.71) MEN1KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL141719 0.80 MAPT (0.63) MEN1KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL15138675 0.80 ALDH1A1 (0.67) MEN1KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL140748 0.80 MAPT (0.63) MEN1KMT2AALDH1A1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9164382-B2 Photorefractive composite, spatial light modulator, and hologram display device using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-10-20 US claimed
US-9097970-B2 Photorefractive composite, spatial light modulator, and hologram display device using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-08-04 US claimed
US-20130148181-A1 PHOTOREFRACTIVE COMPOSITE, SPATIAL LIGHT MODULATOR, AND HOLOGRAM DISPLAY DEVICE USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-06-13 US claimed
US-20130148180-A1 PHOTOREFRACTIVE COMPOSITE, SPATIAL LIGHT MODULATOR, AND HOLOGRAM DISPLAY DEVICE USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-06-13 US claimed
US-9500932-B2 Fast-response photorefractive polymer element NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGY (JP) 2016-11-22 US disclosed
US-9500932-B2 Fast-response photorefractive polymer element NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGY (JP) 2016-11-22 US disclosed
US-9436060-B2 Islands-in-sea type photorefractive polymer composite, and photorefractive device and optical device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-09-06 US disclosed
US-9164382-B2 Photorefractive composite, spatial light modulator, and hologram display device using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-10-20 US disclosed
US-9164382-B2 Photorefractive composite, spatial light modulator, and hologram display device using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-10-20 US disclosed
US-9134550-B2 Photorefractive polymer composite, and photorefractive device and hologram display device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-09-15 US disclosed
US-20150227019-A1 FAST-RESPONSE PHOTOREFRACTIVE POLYMER ELEMENT NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGY (JP) 2015-08-13 US disclosed
US-20150227019-A1 FAST-RESPONSE PHOTOREFRACTIVE POLYMER ELEMENT NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGY (JP) 2015-08-13 US disclosed
WO-2008013774-A2 NON-LINEAR OPTICAL DEVICE WITH LONG GRATING PERSISTENCY NITTO DENKO CORPORATION (JP) 2008-01-31 WO disclosed
WO-2008013775-A2 NON-LINEAR OPTICAL DEVICE SENSITIVE TO GREEN LASER NITTO DENKO CORPORATION (JP) 2008-01-31 WO disclosed
US-7186781-B2 Fullerene-containing polymer, producing method thereof, and photorefractive composition NITTO DENKO CORPORATION (JP) 2007-03-06 US disclosed
US-6280884-B1 HOLOGRAPHIC STORAGE IN PHOTOREFRACTIVE POLYMERIC OPTICAL ARTICLE, EXPOSURE TO ELECTROMAGNETIC RADIATION WITH INTERSECTING BEAMS INTERNATIONAL BUSINESS MACHINES CORPORATION 2001-08-28 US disclosed
US-20010015809-A1 HOMODYNE INTERFEROMETER USING PHOTOREFRACTIVE POLYMER COMPOSITE AND METHOD OF SENSING MATERIAL CALIFORNIA, UNIVERSITY, OF, REGENTS OF THE, THE 2001-08-23 US disclosed
US-5759725-A Photoconductors and electrophotographic photoreceptors containing amorphous fullerenes KABUSHIKI KAISHA TOSHIBA (JP) 1998-06-02 US disclosed
US-5719690-A Photorefractive glass article INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1998-02-17 US disclosed
US-5361148-A Apparatus for photorefractive two beam coupling INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1994-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130148181-A1 PHOTOREFRACTIVE COMPOSITE, SPATIAL LIGHT MODULATOR, AND HOLOGRAM DISPLAY DEVICE USING THE SAME CRY1, HTR3D, GRK1 MEN1 3600/4885KMT2A 2226/4885ALDH1A1 59/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.