Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.49 |
| ▸ | MAOA | P21397 | 6/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKLR | P30613 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2733818 | 0.89 | ALDH1A1 (0.51) | MAOBMAOAMAPTNPC1TP53 | |
| SCHEMBL745193 | 0.78 | PKM (0.54) | MAOBMAOATSHRPKMMAPT | |
| SCHEMBL30627606 | 0.78 | PKM (0.54) | MAOBMAOATSHRPKMMAPT | |
| SCHEMBL16470745 | 0.74 | MAOB (0.53) | MAOBMAOATSHRPKMMAPT | |
| SCHEMBL16470744 | 0.74 | MAOB (0.53) | MAOBMAOATSHRPKMMAPT | |
| SCHEMBL2090955 | 0.74 | MAOB (0.53) | MAOBMAOATSHRPKMMAPT | |
| SCHEMBL14088714 | 0.73 | MAOB (0.62) | MAOBMAOATSHRMAPTNPC1 | |
| SCHEMBL15982325 | 0.73 | MAPT (0.53) | MAOBMAOAPKMMAPTNPC1 | |
| SCHEMBL14964120 | 0.73 | MAPT (0.53) | MAOBMAOAPKMMAPTNPC1 | |
| SCHEMBL15982627 | 0.73 | MAPT (0.53) | MAOBMAOAPKMMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214541-A1 | COMPOSITIONS AND METHODS FOR INDUCING OSTEOGENESIS | IRM LLC (BM) | 2008-09-04 | — | — | US | disclosed |
| US-7273864-B2 | Compositions and methods for inducing osteogenesis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214541-A1 | COMPOSITIONS AND METHODS FOR INDUCING OSTEOGENESIS | BMP2, BMP4, BMP6 | MAOB 4744/4885MAOA 4640/4885TRPV1 4729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.