Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27153773 | 0.83 | DDB1 (0.45) | L3MBTL1ALDH1A1MAPK1ALOX15GAA | |
| SCHEMBL13106354 | 0.79 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1MAPK1ALOX15GAA | |
| SCHEMBL13106356 | 0.79 | ESR1 (0.43) | L3MBTL1ALDH1A1MAPK1LMNAMAPK8 | |
| SCHEMBL13106346 | 0.77 | LMNA (0.43) | L3MBTL1ALDH1A1MAPK1CA12CA9 | |
| SCHEMBL27140925 | 0.75 | JAK2 (0.35) | L3MBTL1LMNATP53THRBTLR9 | |
| SCHEMBL31583269 | 0.75 | L3MBTL1 (0.34) | L3MBTL1ALDH1A1LMNATP53THRB | |
| SCHEMBL26637934 | 0.75 | LMNA (0.37) | L3MBTL1ALDH1A1GAACYP1B1LMNA | |
| SCHEMBL15995385 | 0.75 | DDB1 (0.38) | L3MBTL1ALDH1A1LMNATP53THRB | |
| SCHEMBL30706223 | 0.75 | LMNA (0.37) | L3MBTL1ALDH1A1GAACYP1B1LMNA | |
| SCHEMBL15995629 | 0.75 | LMNA (0.34) | L3MBTL1GAALMNATP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194661-A1 | Antifungal Triazole Derivatives | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194661-A1 | Antifungal Triazole Derivatives | ERG28, CYP51A1, CYP3A43 | L3MBTL1 4421/4885ALDH1A1 2752/4885MAPK1 4156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.