Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14270281 | 0.81 | RAB9A (0.47) | RAB9ANPC1GAAL3MBTL1SLC13A5 | |
| SCHEMBL16674489 | 0.79 | ADRB2 (0.49) | ALDH1A1LMNAKDM4EALOX15TP53 | |
| SCHEMBL28287211 | 0.76 | SIGMAR1 (0.60) | RAB9ANPC1SLC13A5MAPTALDH1A1 | |
| SCHEMBL4969194 | 0.76 | SLC13A5 (0.46) | RAB9ANPC1GAAL3MBTL1SLC13A5 | |
| SCHEMBL1532698 | 0.76 | SLC13A5 (0.49) | RAB9ANPC1GAAL3MBTL1SLC13A5 | |
| SCHEMBL19245042 | 0.75 | S1PR1 (0.59) | RAB9ANPC1GAAL3MBTL1MAPT | |
| SCHEMBL22558673 | 0.74 | SLC13A5 (0.50) | RAB9ANPC1GAAL3MBTL1SLC13A5 | |
| SCHEMBL3399680 | 0.74 | LMNA (0.52) | RAB9ANPC1GAAL3MBTL1SLC13A5 | |
| SCHEMBL21084402 | 0.73 | ADRB2 (0.48) | ALOX15ADRB2HTR2A | |
| SCHEMBL29272968 | 0.73 | SLC13A5 (0.46) | RAB9ANPC1GAAL3MBTL1SLC13A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008106204-A1 | MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X-PHARMACEUTICALS, INC. (US) | 2008-09-04 | — | — | WO | disclosed |