Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.67 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.67 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.67 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.66 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.66 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.66 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.66 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.66 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.66 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.66 |
| ▸ | DRD4 | P21917 | 6/20 | 0.65 |
| ▸ | DRD2 | P14416 | 4/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14082317 | 0.88 | KMT2A (0.62) | SIGMAR1TMEM97SLC6A12MCHR1CYP1A2 | |
| SCHEMBL7218186 | 0.86 | DRD4 (0.86) | SIGMAR1TMEM97SLC6A12MCHR1CYP1A2 | |
| SCHEMBL694949 | 0.86 | SIGMAR1 (0.82) | SIGMAR1TMEM97SLC6A12MCHR1CYP1A2 | |
| SCHEMBL2073964 | 0.86 | PRKAA2 (0.78) | SIGMAR1TMEM97SLC6A12MCHR1CYP1A2 | |
| SCHEMBL14082643 | 0.84 | DRD4 (0.67) | SIGMAR1TMEM97SLC6A12MCHR1CYP1A2 | |
| SCHEMBL14082141 | 0.84 | TMEM97 (0.63) | SIGMAR1TMEM97SLC6A12MCHR1CYP1A2 | |
| SCHEMBL61848 | 0.84 | TMEM97 (0.83) | SIGMAR1TMEM97SLC6A12MCHR1CYP1A2 | |
| SCHEMBL14082199 | 0.83 | MEN1 (0.65) | MCHR1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2070563 | 0.83 | SIGMAR1 (0.74) | SIGMAR1TMEM97SLC6A12MCHR1CYP1A2 | |
| SCHEMBL61850 | 0.83 | DRD2 (0.66) | SIGMAR1TMEM97SLC6A12MCHR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200524-A1 | Amide compounds as ion channel ligands and uses thereof | KELLY MICHAEL G | 2008-08-21 | — | — | US | disclosed |
| US-20080200524-A1 | Amide compounds as ion channel ligands and uses thereof | KELLY MICHAEL G | 2008-08-21 | — | — | US | disclosed |
| US-7338950-B2 | Amide compounds as ion channel ligands and uses thereof | RENOVIS, INC. (US) | 2008-03-04 | — | — | US | disclosed |
| US-7338950-B2 | Amide compounds as ion channel ligands and uses thereof | RENOVIS, INC. (US) | 2008-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200524-A1 | Amide compounds as ion channel ligands and uses thereof | TRPV1, TRPA1, TRPV2 | SIGMAR1 483/4885TMEM97 578/4885SLC6A12 2392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.