SCHEMBL1408765

SCHEMBL1408765

CCCCCC(O)N1CCNCC1

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.42
GNAI3 P08754 8/20 0.41
GNAO1 P09471 8/20 0.41
GNAI1 P63096 8/20 0.41
GPR84 Q9NQS5 3/20 0.34
SPHK1 Q9NYA1 1/20 0.34
FFAR1 O14842 1/20 0.34
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11117641 0.98 GNAI3 (0.43) SIGMAR1GNAI3GNAO1GNAI1GPR84
SCHEMBL21581265 0.98 GNAI3 (0.43) SIGMAR1GNAI3GNAO1GNAI1GPR84
SCHEMBL1409000 0.94 SIGMAR1 (0.47) SIGMAR1GNAI3GNAO1GNAI1
SCHEMBL27862639 0.87 GNAI3 (0.38) SIGMAR1GNAI3GNAO1GNAI1GPR84
SCHEMBL1408997 0.86 SIGMAR1 (0.39) SIGMAR1GNAI3GNAO1GNAI1
SCHEMBL3932573 0.86 GPR84 (0.40) GPR84SPHK1FFAR1LMNA
SCHEMBL21581300 0.85 LMNA (0.38) SIGMAR1GNAI3GNAO1GNAI1GPR84
Hydrochloric Acid SCHEMBL6956666 0.84 SIGMAR1 (0.38) SIGMAR1GNAI3GNAO1GNAI1
Methane SCHEMBL2871267 0.84 SIGMAR1 (0.38) SIGMAR1GNAI3GNAO1GNAI1
SCHEMBL8972636 0.84 GPR84 (0.43) GPR84SPHK1FFAR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2295438-B2 PROCESS FOR PRODUCING HYDROXYALKYLTRIETHYLENEDIAMINE COMPOUND, AND CATALYST COMPOSITION FOR THE PRODUCTION OF POLYURETHANE RESIN USING THE HYDROXYALKYLTRIETHYLENEDIAMINE COMPOUND TOSOH CORP (JP) 2025-03-26 EP disclosed
WO-2023071601-A1 DESLORATADINE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 天津市昕晨投资发展有限公司 2023-05-04 WO disclosed
EP-3575289-B1 ALKANOLAMINE, FRICTION-REDUCING AGENT, AND LUBRICATING OIL COMPOSITION TOSOH CORP (JP) 2023-04-19 EP disclosed
CN-115385892-A Desloratadine derivative, preparation method and application thereof 天津市昕晨投资发展有限公司 2022-11-25 CN disclosed
US-10927084-B2 Alkanolamine, friction-reducing agent, and lubricating oil composition TOSOH CORPORATION (JP) 2021-02-23 US disclosed
US-20200039942-A1 ALKANOLAMINE, FRICTION-REDUCING AGENT, AND LUBRICATING OIL COMPOSITION TOSOH CORPORATION (JP) 2020-02-06 US disclosed
EP-3575289-A1 ALKANOLAMINE, FRICTION-REDUCING AGENT, AND LUBRICATING OIL COMPOSITION Tosoh Corporation (JP) 2019-12-04 EP disclosed
WO-2017030814-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF BROMODOMAIN-CONTAINING PROTEINS Arvinas, Inc. (US) 2017-02-23 WO disclosed
EP-2295438-B1 PROCESS FOR PRODUCING HYDROXYALKYLTRIETHYLENEDIAMINE COMPOUND, AND CATALYST COMPOSITION FOR THE PRODUCTION OF POLYURETHANE RESIN USING THE HYDROXYALKYLTRIETHYLENEDIAMINE COMPOUND TOSOH CORP (JP) 2015-03-18 EP disclosed
US-20110077376-A1 PROCESS FOR PRODUCING HYDROXYALKYLTRIETHYLENEDIAMINE, AND CATALYST COMPOSITION FOR THE PRODUCTION OF POLYURETHANE RESIN USING IT TOSOH CORPORATION (JP) 2011-03-31 US disclosed
EP-2295438-A1 PROCESS FOR PRODUCING HYDROXYALKYLTRIETHYLENEDIAMINE COMPOUND, AND CATALYST COMPOSITION FOR THE PRODUCTION OF POLYURETHANE RESIN USING THE HYDROXYALKYLTRIETHYLENEDIAMINE COMPOUND Tosoh Corporation (JP) 2011-03-16 EP disclosed
US-4455168-A CONTAINING A HETEROCYCLIC, HYDROXY AMINE OR AMIDE RICOH COMPANY, LTD. (JP) 1984-06-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200039942-A1 ALKANOLAMINE, FRICTION-REDUCING AGENT, AND LUBRICATING OIL COMPOSITION APOB, HRH3, PHOSPHO1 SIGMAR1 25/4885GNAI3 3257/4885GNAO1 2390/4885
US-10927084-B2 Alkanolamine, friction-reducing agent, and lubricating oil composition APOB, HRH3, PHOSPHO1 SIGMAR1 25/4885GNAI3 3257/4885GNAO1 2390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.