Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HPSE | Q9Y251 | 6/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14089894 | 0.93 | ESR1 (0.50) | ESR1HPSEIMPDH2MAPTIMPDH1 | |
| Hydrochloric Acid SCHEMBL3363806 | 0.91 | ESR1 (0.49) | ESR1HPSEIMPDH2MAPTIMPDH1 | |
| SCHEMBL14400800 | 0.85 | HTR3E (0.46) | ESR1HPSEIMPDH2MAPTIMPDH1 | |
| SCHEMBL14089905 | 0.84 | ESR1 (0.45) | ESR1IMPDH2MAPTIMPDH1LMNA | |
| SCHEMBL14089909 | 0.81 | MEN1 (0.42) | IMPDH2MAPTIMPDH1ALDH1A1HPGD | |
| SCHEMBL14089903 | 0.80 | IMPDH2 (0.40) | TDP1IMPDH2MAPTIMPDH1LMNA | |
| SCHEMBL6748327 | 0.78 | ESR1 (0.50) | ESR1TDP1IMPDH2MAPTIMPDH1 | |
| Hydrochloric Acid SCHEMBL3362652 | 0.77 | ESR1 (0.49) | ESR1TDP1IMPDH2MAPTIMPDH1 | |
| SCHEMBL14599577 | 0.76 | ESR1 (0.51) | ESR1TDP1IMPDH2MAPTIMPDH1 | |
| SCHEMBL14089900 | 0.76 | NQO2 (0.49) | TDP1MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410999-B2 | Compounds, methods and compositions useful for the treatment of bovine viral diarrhea virus (BVDV) infection and hepatitis C virus (HCV) infection | UNIVERSITY OF NORTH CAROLINIA AT CHAPEL HILL (US) | 2008-08-12 | — | — | US | disclosed |
| US-20070072877-A1 | Compounds, methods and compositions useful for the treatment of bovine viral diarrhea virus (BVDV) infection and hepatitis C virus (HCV) infection | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072877-A1 | Compounds, methods and compositions useful for the treatment of bovine viral diarrhea virus (BVDV) infection and hepatitis C virus (HCV) infection | OAT, GYS2, HCCS | ESR1 2613/4885TDP1 3743/4885RAB9A 3027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.