Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 9/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 8/20 | 0.40 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14089892 | 0.95 | AAK1 (0.44) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| Hydrochloric Acid SCHEMBL3363887 | 0.93 | AAK1 (0.44) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL14089905 | 0.82 | ESR1 (0.45) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL14089906 | 0.81 | ESR1 (0.44) | ALDH1A1MAPTHPGDIMPDH2IMPDH1 | |
| SCHEMBL6752575 | 0.80 | SLC9A1 (0.40) | MEN1ALDH1A1KMT2AAAK1 | |
| SCHEMBL6751883 | 0.80 | AAK1 (0.46) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL14089903 | 0.78 | IMPDH2 (0.40) | ALDH1A1MAPTIMPDH2IMPDH1 | |
| Hydrochloric Acid SCHEMBL6859794 | 0.78 | IMPDH2 (0.61) | MEN1KMT2AAAK1IMPDH2IMPDH1 | |
| SCHEMBL6170236 | 0.77 | AAK1 (0.68) | AAK1IMPDH2IMPDH1 | |
| SCHEMBL1184403 | 0.76 | KMT2A (0.57) | MEN1ALDH1A1MAPTKMT2AIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410999-B2 | Compounds, methods and compositions useful for the treatment of bovine viral diarrhea virus (BVDV) infection and hepatitis C virus (HCV) infection | UNIVERSITY OF NORTH CAROLINIA AT CHAPEL HILL (US) | 2008-08-12 | — | — | US | disclosed |
| US-20070072877-A1 | Compounds, methods and compositions useful for the treatment of bovine viral diarrhea virus (BVDV) infection and hepatitis C virus (HCV) infection | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072877-A1 | Compounds, methods and compositions useful for the treatment of bovine viral diarrhea virus (BVDV) infection and hepatitis C virus (HCV) infection | OAT, GYS2, HCCS | MEN1 4855/4885ALDH1A1 493/4885MAPT 1442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.