Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | LAP3 | P28838 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4187674 | 0.85 | FDPS (0.41) | TGFBR1MMP1MMP2CA12CA1 | |
| SCHEMBL6103610 | 0.82 | FDPS (0.44) | TGFBR1LAP3FDPS | |
| SCHEMBL4184803 | 0.80 | FDPS (0.47) | LAP3FDPS | |
| SCHEMBL14937909 | 0.78 | MMP1 (0.44) | TGFBR1LAP3MMP1MMP2CA12 | |
| SCHEMBL4629779 | 0.75 | TGFBR1 (0.44) | TGFBR1LAP3MMP1MMP2CA12 | |
| SCHEMBL14368418 | 0.74 | TGFBR1 (0.44) | TGFBR1LAP3MMP1MMP2CA12 | |
| SCHEMBL11695059 | 0.74 | LAP3 (0.43) | LAP3MMP1MMP2CA12CA1 | |
| SCHEMBL976101 | 0.74 | TGFBR1 (0.42) | TGFBR1LAP3MMP1MMP2CA12 | |
| SCHEMBL8384172 | 0.73 | TSHR (0.47) | LAP3MMP1MMP2CA12CA1 | |
| SCHEMBL8847175 | 0.73 | TGFBR1 (0.40) | TGFBR1LAP3MMP1MMP2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2294118-A1 | METHOD OF MAKING LIGAND FUNCTIONALIZED SUBSTRATES | 3M Innovative Properties Company (US) | 2011-03-16 | — | — | EP | disclosed |
| US-20100041790-A1 | SELF-ETCHING DENTAL MATERIALS BASED ON (METH)ACRYLAMIDE PHOSPHATES | IVOCLAR VIVADENT AG (LI) | 2010-02-18 | — | — | US | disclosed |
| WO-2009148869-A1 | METHOD OF MAKING LIGAND FUNCTIONALIZED SUBSTRATES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-12-10 | — | — | WO | disclosed |
| US-7622538-B2 | Polymerizable dental material, characterized in that it contains at least one (meth)acrylamide phosphate; adhesives, coating materials and composites for dental purposes; hydrolysis-stable | IVOCLAR VIVADENT AG (LI) | 2009-11-24 | — | — | US | disclosed |
| EP-1674066-B1 | Self-etching dental materials based on (meth)acrylamidophosphates | IVOCLAR VIVADENT AG (LI) | 2008-08-13 | — | — | EP | disclosed |
| EP-1674066-A1 | Self-etching dental materials based on (meth)acrylamidophosphates | Ivoclar Vivadent AG (LI) | 2006-06-28 | — | — | EP | disclosed |
| US-20060135719-A1 | Self-etching dental materials based on (METH) acrylamide phosphates | IVOCLAR VIVADENT AG (LI) | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041790-A1 | SELF-ETCHING DENTAL MATERIALS BASED ON (METH)ACRYLAMIDE PHOSPHATES | MSR1, C1R, HRH3 | TGFBR1 1320/4885LAP3 1526/4885MMP1 4450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.