SCHEMBL14937909

SCHEMBL14937909

C=C(C)C(=O)NC(CC)CP(=O)(O)O

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 2/20 0.44
MMP2 P08253 2/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
MMP8 P22894 1/20 0.44
CA9 Q16790 1/20 0.44
TGFBR1 P36897 1/20 0.41
LAP3 P28838 1/20 0.36
MMP3 P08254 1/20 0.35
FNTA P49354 1/20 0.31
FNTB P49356 1/20 0.31
HTT P42858 1/20 0.31
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14368418 0.91 TGFBR1 (0.44) MMP1MMP2CA12CA1CA2
SCHEMBL2552690 0.86 TGFBR1 (0.39) MMP1MMP2CA12CA1CA2
SCHEMBL2555697 0.83 FDPS (0.42) MMP1MMP2CA12CA1CA2
SCHEMBL11674951 0.82 TGFBR1 (0.50) MMP1MMP2CA12CA1CA2
SCHEMBL2555753 0.82 PLA2G2A (0.44) LAP3FNTAFNTB
SCHEMBL28965466 0.78 CA12 (0.41) MMP1MMP2CA12CA1CA2
SCHEMBL1409013 0.78 TGFBR1 (0.43) MMP1MMP2CA12CA1CA2
SCHEMBL1944434 0.77 TGFBR1 (0.55) MMP1MMP2CA12CA1CA2
SCHEMBL28246144 0.77 TGFBR1 (0.55) MMP1MMP2CA12CA1CA2
SCHEMBL15032661 0.76 TGFBR1 (0.42) MMP1MMP2CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9493598-B2 Polymers having acid and amide moieties, and uses thereof ISP INVESTMENTS LLC (US) 2016-11-15 US claimed
US-20130123147-A1 POLYMERS HAVING ACID AND AMIDE MOIETIES, AND USES THEREOF ISP INVESTMENTS INC. (US) 2013-05-16 US claimed
US-9493598-B2 Polymers having acid and amide moieties, and uses thereof ISP INVESTMENTS LLC (US) 2016-11-15 US disclosed
US-20130123147-A1 POLYMERS HAVING ACID AND AMIDE MOIETIES, AND USES THEREOF ISP INVESTMENTS INC. (US) 2013-05-16 US disclosed