SCHEMBL14094136

SCHEMBL14094136

CCC(C)c1cccc(Cn2nnc3c(=O)[nH]cnc32)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.43
KMT2A Q03164 2/20 0.42
HPGD P15428 9/20 0.41
TSHR P16473 3/20 0.41
ALOX15 P16050 1/20 0.41
MMP13 P45452 1/20 0.41
ALDH1A1 P00352 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C19 P33261 1/20 0.40
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.39
HTT P42858 2/20 0.39
LMNA P02545 1/20 0.39
PKM P14618 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
RAD51 Q06609 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
IDO1 P14902 1/20 0.36
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9475698 0.80 GRM2 (0.51) POLBKMT2AHPGDTSHRALOX15
SCHEMBL9476195 0.77 ADORA3 (0.51) POLBKMT2AHPGDTSHRALOX15
SCHEMBL9475856 0.72 HPGD (0.59) POLBKMT2AHPGDTSHRALDH1A1
SCHEMBL20224894 0.72 ADORA2A (0.46) KMT2AHPGDALDH1A1
SCHEMBL30931879 0.71 PDE8B (0.53) KMT2AHPGDTSHRALOX15ALDH1A1
SCHEMBL9477367 0.71 ADORA3 (0.46) KMT2AHPGDTSHRALOX15ALDH1A1
SCHEMBL9476371 0.70 LMNA (0.53) KMT2AHPGDTSHRALDH1A1MEN1
SCHEMBL9476477 0.68 MEN1 (0.62) KMT2AHPGDTSHRALDH1A1MEN1
SCHEMBL9476624 0.68 TSHR (0.61) POLBKMT2AHPGDTSHRALDH1A1
SCHEMBL21943145 0.68 CYP1A2 (0.40) KMT2AHPGDTSHRALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8771924-B2 Polymerizable composition, lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2014-07-08 US disclosed
US-20080199804-A1 Including free radical binder polymer containing functional group having dipole moment of 3.8 debye; laser computer controlled direct plate making without alkali development; sensitivity, printing durability FUJIFILM CORPORATION (JP) 2008-08-21 US disclosed