Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | STAT1 | P42224 | 1/20 | 0.62 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.60 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14096534 | 0.92 | RAB9A (0.62) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL5445610 | 0.88 | MAPT (0.71) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL14095975 | 0.86 | SIRT2 (0.60) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL14095964 | 0.86 | EPHX1 (0.63) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL3717975 | 0.85 | BCAT2 (0.72) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL3717981 | 0.85 | SIRT2 (0.60) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL3044656 | 0.84 | ALDH1A1 (0.70) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL5448085 | 0.83 | RAB9A (0.50) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL14095973 | 0.83 | SIRT1 (0.59) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL14096350 | 0.83 | SIRT2 (0.56) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207760-A1 | Pharmaceutical Compositions For and Methods of Inhibiting Hcv | ACHILLION PHARMACEUTICALS, INC. (US) | 2008-08-28 | — | — | US | disclosed |
| US-20080207760-A1 | Pharmaceutical Compositions For and Methods of Inhibiting Hcv | ACHILLION PHARMACEUTICALS, INC. (US) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207760-A1 | Pharmaceutical Compositions For and Methods of Inhibiting Hcv | RNASE1, SARS1, EIF2AK2 | ALDH1A1 2930/4885NPC1 886/4885RAB9A 3144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.