Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL464127 | 1.00 | ALDH1A1 (0.47) | ALDH1A1CYP3A4TSHRMAPTTP53 | |
| SCHEMBL464269 | 0.93 | ALDH1A1 (0.47) | ALDH1A1CYP3A4TSHRMAPTTP53 | |
| SCHEMBL13201867 | 0.88 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TSHRMAPTTP53 | |
| SCHEMBL15087458 | 0.87 | CTSK (0.48) | ALDH1A1CYP3A4TSHRMAPTTP53 | |
| SCHEMBL20825664 | 0.85 | EPHX1 (0.56) | ALDH1A1CYP3A4TSHRMAPTTP53 | |
| SCHEMBL13219417 | 0.85 | MEN1 (0.47) | ALDH1A1CYP3A4TSHRMAPTCTSK | |
| SCHEMBL8372704 | 0.84 | CTSB (0.61) | CTSKCTSLCTSBCTSS | |
| SCHEMBL13219700 | 0.84 | CTSK (0.44) | ALDH1A1CYP3A4TSHRMAPTTP53 | |
| SCHEMBL8667196 | 0.82 | TRPM8 (0.54) | ALDH1A1CTSKCTSLCTSBCTSS | |
| SCHEMBL20681662 | 0.81 | CTSL (0.54) | ALDH1A1CYP3A4TSHRCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1958956-A2 | Peptidomimetic protease inhibitors | Vertex Pharmaceuticals Incorporated (US) | 2008-08-20 | — | — | EP | disclosed |