Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14100956 | 0.90 | CYP1A2 (0.39) | ALDH1A1LMNAHTTCYP1A2MCL1 | |
| SCHEMBL4585669 | 0.84 | ALDH1A1 (0.45) | TSHRALDH1A1CYP3A4HPGDHSD17B10 | |
| SCHEMBL16574516 | 0.82 | LTA4H (0.46) | TSHRALDH1A1CYP3A4HPGDHSD17B10 | |
| SCHEMBL4129543 | 0.82 | ALDH1A1 (0.59) | TSHRALDH1A1CYP3A4HPGDHSD17B10 | |
| SCHEMBL7650284 | 0.81 | CYP1A2 (0.54) | TSHRCYP3A4LMNAHTTCYP1A2 | |
| SCHEMBL3978100 | 0.77 | ALDH1A1 (0.70) | TSHRALDH1A1CYP3A4HPGDHSD17B10 | |
| SCHEMBL443084 | 0.77 | CYP1A2 (0.46) | TSHRALDH1A1CYP3A4HPGDHSD17B10 | |
| SCHEMBL2083628 | 0.76 | ALDH1A1 (0.52) | TSHRALDH1A1CYP3A4HPGDHSD17B10 | |
| SCHEMBL24595251 | 0.75 | TSHR (0.52) | TSHRALDH1A1CYP3A4HPGDHSD17B10 | |
| SCHEMBL4590420 | 0.73 | ALDH1A1 (0.48) | TSHRALDH1A1CYP3A4HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080166593-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | US | disclosed |
| US-20080166593-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080166593-A1 | Organic Electroluminescent Devices | OR10J3, DDT, EML4 | TSHR 4469/4885ALDH1A1 610/4885CYP3A4 307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.