SCHEMBL16574516

SCHEMBL16574516

c1ccc(Oc2ccc3ccc4c(Oc5ccccc5)ccc5ccc2c3c54)cc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.46
TSHR P16473 1/20 0.46
HRH1 P35367 1/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 1/20 0.41
GLA P06280 1/20 0.41
MAPT P10636 1/20 0.41
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39
THRB P10828 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TTR P02766 2/20 0.39
ADORA1 P30542 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL443084 0.94 CYP1A2 (0.46) LTA4HTSHRHRH1KMT2AKDM4E
SCHEMBL14101043 0.82 TSHR (0.42) TSHRKMT2AKDM4EGLAMAPT
SCHEMBL29568013 0.82 LTA4H (0.50) LTA4HTSHRHRH1KMT2AKDM4E
SCHEMBL21179294 0.82 CYP1A2 (0.50) LTA4HTSHRKMT2AKDM4EGLA
SCHEMBL6516074 0.79 CYP1A2 (0.52) LTA4HTSHRKMT2AKDM4EGLA
SCHEMBL536544 0.79 LTA4H (0.58) LTA4HTSHRHRH1KMT2AKDM4E
SCHEMBL31529058 0.77 ALDH1A1 (0.52) TSHRKMT2AKDM4EGLAMAPT
SCHEMBL442152 0.77 ALDH1A1 (0.52) TSHRKMT2AKDM4EGLAMAPT
SCHEMBL12128531 0.76 ALDH1A1 (0.34) TSHRKMT2AKDM4EMAPTALDH1A1
SCHEMBL6293916 0.76 CYP1A2 (0.49) TSHRKMT2AKDM4EGLAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10297760-B2 Organic electroluminescent element, compound and material for organic electroluminescent element, used in the same, and light emitting device, display device and illumination device, using the element UDC IRELAND LIMITED (IE) 2019-05-21 US disclosed
US-20180102483-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND AND MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, USED IN THE SAME, AND LIGHT EMITTING DEVICE, DISPLAY DEVICE AND ILLUMINATION DEVICE, USING THE ELEMENT UDC IRELAND LTD (IE) 2018-04-12 US disclosed
US-20180102483-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND AND MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, USED IN THE SAME, AND LIGHT EMITTING DEVICE, DISPLAY DEVICE AND ILLUMINATION DEVICE, USING THE ELEMENT UDC IRELAND LTD (IE) 2018-04-12 US disclosed
US-9812650-B2 Organic electroluminescent element, compound and material for organic electroluminescent element, used in the same, and light emitting device, display device and illumination device, using the element UDC IRELAND LIMITED (IE) 2017-11-07 US disclosed
US-9812650-B2 Organic electroluminescent element, compound and material for organic electroluminescent element, used in the same, and light emitting device, display device and illumination device, using the element UDC IRELAND LIMITED (IE) 2017-11-07 US disclosed
US-20150076462-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND AND MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, USED IN THE SAME, AND LIGHT EMITTING DEVICE, DISPLAY DEVICE AND ILLUMINATION DEVICE, USING THE ELEMENT UDC IRELAND LIMITED (IE) 2015-03-19 US disclosed
US-20150076462-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND AND MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, USED IN THE SAME, AND LIGHT EMITTING DEVICE, DISPLAY DEVICE AND ILLUMINATION DEVICE, USING THE ELEMENT UDC IRELAND LIMITED (IE) 2015-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10297760-B2 Organic electroluminescent element, compound and material for organic electroluminescent element, used in the same, and light emitting device, display device and illumination device, using the element RPS10, RPS20, RPS19 LTA4H 2869/4885TSHR 2402/4885HRH1 1615/4885
US-20180102483-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND AND MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, USED IN THE SAME, AND LIGHT EMITTING DEVICE, DISPLAY DEVICE AND ILLUMINATION DEVICE, USING THE ELEMENT RPS10, RPS20, RPS19 LTA4H 2869/4885TSHR 2402/4885HRH1 1615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.