Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24542515 | 0.85 | GLS (0.42) | SMN1; SMN2KDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL1935742 | 0.82 | AKT1 (0.43) | SMN1; SMN2KDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL20131479 | 0.80 | SMN1; SMN2 (0.59) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL4798737 | 0.79 | ALOX5 (0.58) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL1684467 | 0.79 | PYCR1 (0.42) | SMN1; SMN2KDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL23448763 | 0.78 | HRH3 (0.44) | SMN1; SMN2KDM4EALDH1A1HRH3RAB9A | |
| SCHEMBL3365028 | 0.77 | L3MBTL1 (0.43) | SMN1; SMN2 | |
| SCHEMBL1935308 | 0.77 | PPARG (0.46) | SMN1; SMN2KDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL25546128 | 0.77 | HSP90AA1 (0.43) | SMN1; SMN2KDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL2229917 | 0.77 | MTOR (0.48) | SMN1; SMN2KDM4EALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |