Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14101227 | 0.99 | CHRM3 (0.40) | FDPSKCNH2CHRM3CHRM2CHRM4 | |
| SCHEMBL14101291 | 0.85 | ACHE (0.38) | CHRM3CHRM2CHRM4CHRM1ALDH1A1 | |
| SCHEMBL14101035 | 0.83 | ALDH1A1 (0.40) | CHRM3CHRM2CHRM4CHRM1ALDH1A1 | |
| SCHEMBL4742907 | 0.82 | CHRM3 (0.41) | KCNH2CHRM3CHRM2CHRM4CHRM1 | |
| SCHEMBL4741476 | 0.81 | KCNH2 (0.40) | KCNH2CHRM3CHRM2CHRM1ALDH1A1 | |
| SCHEMBL4739872 | 0.80 | KCNH2 (0.39) | KCNH2CHRM3CHRM2CHRM4CHRM1 | |
| SCHEMBL4783504 | 0.80 | LMNA (0.39) | KCNH2CHRM3CHRM2CHRM1ALDH1A1 | |
| SCHEMBL1109850 | 0.80 | CHRM3 (0.40) | FDPSKCNH2CHRM3CHRM2CHRM4 | |
| SCHEMBL1109851 | 0.80 | CHRM3 (0.40) | FDPSKCNH2CHRM3CHRM2CHRM4 | |
| SCHEMBL1110599 | 0.80 | CHRM3 (0.40) | FDPSKCNH2CHRM3CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |