Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14101285 | 0.85 | FDPS (0.40) | ACHEALDH1A1POLBCHRM3CHRM2 | |
| SCHEMBL14101227 | 0.84 | CHRM3 (0.40) | ALDH1A1POLBCHRM3CHRM2CHRM4 | |
| SCHEMBL4741477 | 0.82 | LMNA (0.38) | ACHEALDH1A1CHRM3CHRM2CHRM4 | |
| SCHEMBL14101035 | 0.81 | ALDH1A1 (0.40) | ALDH1A1POLBCHRM3CHRM2CHRM4 | |
| SCHEMBL4742907 | 0.81 | CHRM3 (0.41) | ALDH1A1POLBCHRM3CHRM2CHRM4 | |
| SCHEMBL3227969 | 0.73 | CHRM3 (0.41) | CHRM3CHRM2CHRM4CHRM1SIGMAR1 | |
| SCHEMBL14101197 | 0.71 | ATM (0.43) | ALDH1A1CHRM3CHRM2CHRM4CHRM1 | |
| SCHEMBL27795411 | 0.71 | CHRM3 (0.40) | CHRM3CHRM2CHRM4CHRM1SIGMAR1 | |
| SCHEMBL4783504 | 0.71 | LMNA (0.39) | ALDH1A1CHRM3CHRM2CHRM1 | |
| SCHEMBL3217762 | 0.70 | CHRM3 (0.42) | CHRM3CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |