Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TSPO | P30536 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14101694 | 0.84 | NPSR1 (0.49) | MAPTALDH1A1TSPOGAANPSR1 | |
| SCHEMBL16135913 | 0.77 | RXFP1 (0.55) | MAPTALDH1A1GAAKDM4ELMNA | |
| SCHEMBL14101693 | 0.75 | RAB9A (0.50) | MAPTALDH1A1GAAKDM4ENPSR1 | |
| SCHEMBL16336272 | 0.73 | TP53 (0.56) | MAPTALDH1A1TSPOLMNAHPGD | |
| SCHEMBL7750505 | 0.72 | TSPO (0.61) | MAPTALDH1A1TSPOGAAKDM4E | |
| SCHEMBL600372 | 0.71 | TSPO (0.78) | MAPTALDH1A1TSPOKDM4EPOLB | |
| SCHEMBL16135890 | 0.71 | GAA (0.41) | MAPTALDH1A1GAAKDM4ELMNA | |
| SCHEMBL16110079 | 0.69 | RXFP1 (0.68) | MAPTALDH1A1GAAKDM4EHPGD | |
| SCHEMBL16311097 | 0.68 | TSHR (0.68) | MAPTALDH1A1GAAHPGDNPSR1 | |
| SCHEMBL17122538 | 0.68 | ALKBH5 (0.44) | MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |