Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14101694 | 0.87 | NPSR1 (0.49) | MAPTALDH1A1GAANPSR1RXFP1 | |
| SCHEMBL16135913 | 0.81 | RXFP1 (0.55) | MAPTALDH1A1GAARXFP1POLB | |
| SCHEMBL14101695 | 0.75 | MAPT (0.52) | MAPTALDH1A1GAANPSR1RXFP1 | |
| SCHEMBL16336272 | 0.74 | TP53 (0.56) | MAPTALDH1A1NPSR1POLBCFTR | |
| SCHEMBL16135890 | 0.74 | GAA (0.41) | MAPTALDH1A1GAARXFP1POLB | |
| SCHEMBL14290280 | 0.72 | RAB9A (0.53) | RAB9ANPC1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL16136033 | 0.71 | KMT2A (0.47) | MAPTALDH1A1L3MBTL1GAANPSR1 | |
| SCHEMBL20379747 | 0.71 | L3MBTL1 (0.71) | RAB9ANPC1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL8864636 | 0.70 | HPGD (0.60) | RAB9ANPC1MAPTALDH1A1HTT | |
| SCHEMBL6136897 | 0.70 | RORC (0.54) | PTPN11POLBKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |