SCHEMBL2453399

SCHEMBL2453399

CC(C)CCC[C@@H](C)[C@H]1CC(=O)[C@@]2(C)[C@@H]3CC[C@H]4C(C)(C)CCC[C@@]45C[C@]35CC[C@]12C

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CDC25A P30304 16/20 0.40
▸ CDC25B P30305 14/20 0.40
▸ NPC1L1 Q9UHC9 1/20 0.37
▸ EBP Q15125 2/20 0.36
▸ HSD11B1 P28845 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2453402 1.00 CDC25A (0.40) CDC25ACDC25BNPC1L1EBPHSD11B1
SCHEMBL300737 0.80 ACLY (0.48) CDC25ACDC25BEBPHSD11B1
SCHEMBL1050397 0.80 ACLY (0.48) CDC25ACDC25BEBPHSD11B1
SCHEMBL2450676 0.77 CDC25A (0.46) CDC25ACDC25BNPC1L1EBP
SCHEMBL2450675 0.77 CDC25A (0.46) CDC25ACDC25BNPC1L1EBP
SCHEMBL14116745 0.76 CDC25A (0.51) CDC25ACDC25BEBPHSD11B1
SCHEMBL29934951 0.69 CDC25A (0.59) CDC25ACDC25BEBPHSD11B1
SCHEMBL3285801 0.65 ACLY (0.61) EBPHSD11B1
SCHEMBL3285804 0.65 ACLY (0.61) EBPHSD11B1
SCHEMBL14773157 0.64 ACLY (0.33) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013036684-A1 COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS SATORI PHARMACEUTICALS, INC (US) 2013-03-14 — — WO disclosed
US-20130060013-A1 Compounds useful for treating neurodegenerative disorders SATORI PHARMACEUTICALS, INC. (US) 2013-03-07 — — US disclosed
EP-2542085-A1 COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS Satori Pharmaceuticals, Inc. (US) 2013-01-09 — — EP disclosed
US-20110251379-A1 COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS SATORI PHARMACEUTICALS, INC. (US) 2011-10-13 — — US disclosed
WO-2011109657-A1 COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS SATORI PHARMACEUTICALS, INC. (US) 2011-09-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130060013-A1 Compounds useful for treating neurodegenerative disorders SNCA, HTT, CLN6 CDC25A 3836/4885CDC25B 4224/4885NPC1L1 96/4885
US-20110251379-A1 COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS CLN6, NLN, ACHE CDC25A 4241/4885CDC25B 4330/4885NPC1L1 176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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