SCHEMBL14129043

SCHEMBL14129043

C(=N/c1ccc(/N=C/c2ccccc2)[nH]1)\c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
G6PD P11413 2/20 0.44
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
LIG1 P18858 1/20 0.42
LIG3 P49916 1/20 0.42
LIG4 P49917 1/20 0.42
KDM4E B2RXH2 4/20 0.40
ALDH1A1 P00352 3/20 0.40
MAPT P10636 3/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
HPGD P15428 2/20 0.40
PTGS2 P35354 2/20 0.40
NOX1 Q9Y5S8 1/20 0.40
USP2 O75604 1/20 0.40
POLB P06746 1/20 0.40
CASP1 P29466 1/20 0.40
BRCA1 P38398 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13084384 0.72 ALDH1A1 (0.63) LMNAL3MBTL1CA1CA2KDM4E
SCHEMBL1710167 0.72 LMNA (0.59) LMNAL3MBTL1CA1CA2KDM4E
SCHEMBL1870853 0.72 LMNA (0.59) LMNAL3MBTL1CA1CA2KDM4E
SCHEMBL3417678 0.72 CA2 (0.69) LMNAL3MBTL1CA1CA2KDM4E
SCHEMBL59999 0.72 ALDH1A1 (0.63) LMNAL3MBTL1CA1CA2KDM4E
SCHEMBL3417682 0.72 CA2 (0.69) LMNAL3MBTL1CA1CA2KDM4E
SCHEMBL12633216 0.72 LMNA (0.59) LMNAL3MBTL1CA1CA2KDM4E
SCHEMBL60000 0.72 ALDH1A1 (0.63) LMNAL3MBTL1CA1CA2KDM4E
Ammonia Solution, Strong SCHEMBL2273341 0.70 ALDH1A1 (0.61) LMNAL3MBTL1CA1CA2KDM4E
SCHEMBL14524455 0.70 LMNA (0.55) LMNAL3MBTL1CA1CA2LIG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120302720-A1 Novel Polyazomethine SOKEN CHEMICAL & ENGINEERING CO., LTD. (JP) 2012-11-29 US disclosed