Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.47 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 2/20 | 0.42 |
| ▸ | GABRD | O14764 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.42 |
| ▸ | GABRE | P78334 | 2/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11127655 | 0.78 | CES2 (0.41) | LMNAHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL463465 | 0.78 | EGLN1 (0.53) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL8397315 | 0.76 | EGLN1 (0.69) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| SCHEMBL1435946 | 0.76 | — | — | |
| SCHEMBL10143323 | 0.76 | LMNA (0.50) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL11859340 | 0.75 | EGLN1 (0.43) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| SCHEMBL15823996 | 0.75 | LMNA (0.43) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| SCHEMBL1986431 | 0.74 | GABRP (0.54) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| SCHEMBL27375102 | 0.74 | — | — | |
| Succinic Acid SCHEMBL21081056 | 0.74 | LMNA (0.64) | EGLN1LMNAALKBH5SUCNR1SLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022229-B2 | Process for the preparation of alkyl 5-(dicarboximido) levulinate and alkyl 4-oxo-pentenoate | ALFA-SYNTHON AB (SE) | 2011-09-20 | — | — | US | disclosed |
| EP-1833790-B1 | PROCESS FOR THE PREPARATION OF ALKYL 5-(DICARBOXIMIDO)LEVULINATE AND ALKYL 4-OXO-PENTENOATE | ALFA SYNTHON AB (SE) | 2011-03-16 | — | — | EP | disclosed |
| US-20080027233-A1 | Process for the Preparation of Alkyl 5-(Dicarboximido) Levulinate and Alkyl 4-Oxopentenoate | ESQUIRE AB (SE) | 2008-01-31 | — | — | US | disclosed |
| EP-1833790-A1 | PROCESS FOR THE PREPARATION OF ALKYL 5-(DICARBOXIMIDO)LEVULINATE AND ALKYL 4-OXO-PENTENOATE | Biosynth AB (SE) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006048236-A1 | PROCESS FOR THE PREPARATION OF ALKYL 5- (DICARBOXIMIDO) LEVULINATE AND ALKYL 4-OXO-PENTENOATE | BIOSYNTH AB (SE) | 2006-05-11 | — | — | WO | disclosed |
| US-5907058-A | Synthesis of an acid addition salt of delta-aminolevulinic acid from 5-bromo levulinic acid esters | MIDWEST RESEARCH INSTITUTE (US) | 1999-05-25 | — | — | US | disclosed |