SCHEMBL14132575

SCHEMBL14132575

Cn1c2ccccc2c2cc(-c3cccc(-n4c5ccccc5c5ccccc54)c3)ccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GPR3 P46089 1/20 0.50
▸ L3MBTL1 Q9Y468 4/20 0.47
▸ KDM4E B2RXH2 3/20 0.47
▸ MAPT P10636 2/20 0.47
▸ HPGD P15428 2/20 0.47
▸ HSD17B10 Q99714 2/20 0.47
▸ ALDH1A1 P00352 2/20 0.47
▸ KMT2A Q03164 2/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ HTT P42858 1/20 0.47
▸ ATM Q13315 1/20 0.47
▸ RXRA P19793 1/20 0.42
▸ RXRB P28702 1/20 0.42
▸ PABPC1 P11940 1/20 0.40
▸ ALKBH5 Q6P6C2 1/20 0.40
▸ FTO Q9C0B1 1/20 0.40
▸ KIF11 P52732 1/20 0.40
▸ PGR P06401 1/20 0.40
▸ TSPO P30536 1/20 0.39
▸ NPY5R Q15761 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14649293 1.00 GPR3 (0.50) GPR3L3MBTL1KDM4EMAPTHPGD
SCHEMBL14133047 0.98 GPR3 (0.48) GPR3L3MBTL1KDM4EMAPTHPGD
SCHEMBL21031230 0.97 KDM4E (0.49) GPR3L3MBTL1KDM4EMAPTHPGD
SCHEMBL22906534 0.96 KDM4E (0.47) GPR3L3MBTL1KDM4EMAPTHPGD
SCHEMBL14649295 0.94 KDM4E (0.50) GPR3L3MBTL1KDM4EMAPTHPGD
SCHEMBL14649438 0.94 KDM4E (0.46) GPR3L3MBTL1KDM4EMAPTHPGD
SCHEMBL26049045 0.92 KDM4E (0.44) GPR3L3MBTL1KDM4EMAPTHPGD
SCHEMBL19101097 0.91 KDM4E (0.56) GPR3L3MBTL1KDM4EMAPTHPGD
SCHEMBL14649450 0.91 L3MBTL1 (0.54) GPR3L3MBTL1KDM4EMAPTHPGD
SCHEMBL14649354 0.91 GPR3 (0.41) GPR3L3MBTL1KDM4EMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10777754-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-09-15 — — US disclosed
EP-2910555-B1 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORP (US) 2019-03-27 — — EP disclosed
EP-2551932-B1 Host materials for phosphorescent oleds UNIVERSAL DISPLAY CORP (US) 2018-05-23 — — EP disclosed
US-9502656-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-11-22 — — US disclosed
US-9502656-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-11-22 — — US disclosed
US-9184399-B2 Asymmetric hosts with triaryl silane side chains UNIVERSAL DISPLAY CORPORATION (US) 2015-11-10 — — US disclosed
US-9184399-B2 Asymmetric hosts with triaryl silane side chains UNIVERSAL DISPLAY CORPORATION (US) 2015-11-10 — — US disclosed
US-9142788-B2 Host materials for OLEDs UNIVERSAL DISPLAY CORPORATION (US) 2015-09-22 — — US disclosed
US-9142788-B2 Host materials for OLEDs UNIVERSAL DISPLAY CORPORATION (US) 2015-09-22 — — US disclosed
US-20150243893-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-08-27 — — US disclosed
US-20130119353-A1 TRIPHENYLENE SILANE HOSTS UNIVERSAL DISPLAY CORPORATION (US) 2013-05-16 — — US disclosed
US-20130119353-A1 TRIPHENYLENE SILANE HOSTS UNIVERSAL DISPLAY CORPORATION (US) 2013-05-16 — — US disclosed
US-8409729-B2 Host materials for phosphorescent OLEDs UNIVERSAL DISPLAY CORPORATION (US) 2013-04-02 — — US disclosed
US-8409729-B2 Host materials for phosphorescent OLEDs UNIVERSAL DISPLAY CORPORATION (US) 2013-04-02 — — US disclosed
US-20130026909-A1 HOST MATERIALS FOR PHOSPHORESCENT OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2013-01-31 — — US disclosed
US-20130026909-A1 HOST MATERIALS FOR PHOSPHORESCENT OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2013-01-31 — — US disclosed
EP-2551932-A2 Host materials for phosphorescent oleds Universal Display Corporation (US) 2013-01-30 — — EP disclosed
US-20120298966-A1 Host materials for oled UNIVERSAL DISPLAY CORPORATION (US) 2012-11-29 — — US disclosed
US-20120298966-A1 Host materials for oled UNIVERSAL DISPLAY CORPORATION (US) 2012-11-29 — — US disclosed
WO-2012162325-A1 HOST MATERIALS FOR OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2012-11-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120298966-A1 Host materials for oled OCIAD2, OCIAD1, OSBP2 GPR3 655/4885L3MBTL1 1065/4885KDM4E 3086/4885
US-20130119353-A1 TRIPHENYLENE SILANE HOSTS OCIAD2, OCIAD1, YAP1 GPR3 971/4885L3MBTL1 659/4885KDM4E 3627/4885
US-20130026909-A1 HOST MATERIALS FOR PHOSPHORESCENT OLEDS OSBP2, OCIAD2, OCIAD1 GPR3 380/4885L3MBTL1 1959/4885KDM4E 3835/4885
US-10777754-B2 Organic electroluminescent materials and devices DBF4, ORC3, NUDC GPR3 3953/4885L3MBTL1 2225/4885KDM4E 1719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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