Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26981197 | 0.88 | LTA4H (0.75) | LTA4HMEN1KMT2AGAATEAD3 | |
| SCHEMBL19557301 | 0.88 | LTA4H (0.75) | LTA4HMEN1KMT2AGAATEAD3 | |
| SCHEMBL31305362 | 0.85 | LTA4H (0.71) | LTA4HMEN1KMT2AGAATEAD3 | |
| SCHEMBL29447351 | 0.82 | LTA4H (0.87) | LTA4HMEN1KMT2AGAASIGMAR1 | |
| SCHEMBL5708578 | 0.81 | SIGMAR1 (0.73) | LTA4HMEN1KMT2ASIGMAR1ALDH1A1 | |
| SCHEMBL6393260 | 0.80 | LTA4H (0.84) | LTA4HSIGMAR1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL13273818 | 0.80 | SLC6A3 (0.61) | SIGMAR1MAPTSLC6A3NPSR1 | |
| SCHEMBL13940618 | 0.80 | LTA4H (0.68) | LTA4HMEN1KMT2AGAATEAD3 | |
| Hydrochloric Acid SCHEMBL467279 | 0.79 | SIGMAR1 (0.71) | LTA4HMEN1KMT2ASIGMAR1ALDH1A1 | |
| SCHEMBL7388780 | 0.79 | LTA4H (0.67) | LTA4HMEN1KMT2AGAATEAD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2532662-B1 | SYNTHESIS PROCESS OF DASATINIB AND INTERMEDIATE THEREOF | NANJING CAVENDISH BIO ENGINEERING TECHNOLOGY CO LTD (CN) | 2016-01-27 | — | — | EP | disclosed |
| US-9108954-B2 | Synthesis process of dasatinib and intermediate thereof | NAN JING CAVENDISH BIO-ENGINEERING TECHNOLOGY CO., LTD. (CN) | 2015-08-18 | — | — | US | disclosed |
| US-20130030177-A1 | SYNTHESIS PROCESS OF DASATINIB AND INTERMEDIATE THEREOF | Nan Jing Cavendish Bio-Engineering Technology Co. Ltd. (CN) | 2013-01-31 | — | — | US | disclosed |
| EP-2532662-A1 | SYNTHESIS PROCESS OF DASATINIB AND INTERMEDIATE THEREOF | Nanjing Cavendish Bio-Engineering Technology Co., Ltd. (CN) | 2012-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130030177-A1 | SYNTHESIS PROCESS OF DASATINIB AND INTERMEDIATE THEREOF | ABL1, YES1, ABL2 | LTA4H 3795/4885MEN1 2439/4885KMT2A 1804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.