Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | TP53 | P04637 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.66 |
| ▸ | THPO | P40225 | 2/20 | 0.66 |
| ▸ | MTOR | P42345 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL467279 | 0.98 | SIGMAR1 (0.71) | SIGMAR1SMN1; SMN2TP53CYP1A2CYP2D6 | |
| SCHEMBL26981197 | 0.91 | LTA4H (0.75) | SIGMAR1SMN1; SMN2TP53CYP1A2CYP2D6 | |
| SCHEMBL521127 | 0.91 | SLC6A4 (0.68) | SIGMAR1SMN1; SMN2TP53CYP1A2CYP2D6 | |
| SCHEMBL19557301 | 0.91 | LTA4H (0.75) | SIGMAR1SMN1; SMN2TP53CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL7280212 | 0.90 | SIGMAR1 (0.59) | SIGMAR1SMN1; SMN2TP53CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL9646859 | 0.89 | SIGMAR1 (0.58) | SIGMAR1SMN1; SMN2TP53CYP1A2CYP2D6 | |
| SCHEMBL31305362 | 0.88 | LTA4H (0.71) | SIGMAR1SMN1; SMN2TP53CYP1A2CYP2D6 | |
| SCHEMBL6550825 | 0.86 | SIGMAR1 (1.00) | SIGMAR1LTA4HCCR3POLB | |
| SCHEMBL2962629 | 0.86 | SIGMAR1 (1.00) | SIGMAR1LTA4HCCR3POLB | |
| SCHEMBL29447351 | 0.84 | LTA4H (0.87) | SIGMAR1SMN1; SMN2RAB9ASLC6A3LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060246099-A1 | Compositions containing piperazine compounds | L'OREAL (FR) | 2006-11-02 | — | — | US | disclosed |
| EP-1714639-A1 | Cosmetic compositions containing piperazine derivatives | L'OREAL (FR) | 2006-10-25 | — | — | EP | disclosed |
| US-5281598-A | Psychological disorders | AKZO N.V. (NL) | 1994-01-25 | — | — | US | disclosed |
| EP-0566189-A1 | Psychotropic piperazine derivative | AKZO N.V. (NL) | 1993-10-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060246099-A1 | Compositions containing piperazine compounds | KLF5, CUTA, COL2A1 | SIGMAR1 4633/4885SMN1; SMN2 1159/4885TP53 4003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.