Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1414647 | 0.79 | ESR1 (0.41) | MEN1KMT2A | |
| SCHEMBL11075063 | 0.72 | KMT2A (0.49) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL8813777 | 0.71 | KIF11 (0.50) | NR3C2 | |
| SCHEMBL5528030 | 0.71 | ALDH1A1 (0.43) | MEN1KMT2A | |
| SCHEMBL5255832 | 0.70 | ESR1 (0.59) | MEN1KMT2A | |
| SCHEMBL21495110 | 0.70 | KIF11 (0.43) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL8796837 | 0.70 | KIF11 (0.43) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL4015306 | 0.70 | KCNN4 (0.50) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL909285 | 0.67 | GPR84 (0.47) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL29689517 | 0.67 | GPR84 (0.47) | MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045081-B1 | TRISUBSTITUTED IMIDAZOLE DERIVATIVES, PROCESSES FOR PREPARING THEM, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE | CIBA-GEIGY AG (CH) | 1986-01-08 | — | — | EP | disclosed |
| EP-0045081-A2 | Trisubstituted imidazole derivatives, processes for preparing them, pharmaceutical compositions containing them, and their use | CIBA-GEIGY AG (CH) | 1982-02-03 | — | — | EP | disclosed |