Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.46 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.44 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.44 |
| ▸ | ITGAL | P20701 | 2/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2178184 | 1.00 | CYP3A4 (0.56) | CYP3A4TSHRCYP2D6CYP2C19LMNA | |
| SCHEMBL2195381 | 1.00 | CYP3A4 (0.56) | CYP3A4TSHRCYP2D6CYP2C19LMNA | |
| SCHEMBL19085694 | 0.89 | SLC15A2 (0.53) | CYP3A4TSHRCYP2D6CYP2C19LMNA | |
| SCHEMBL2176441 | 0.85 | CYP3A4 (0.51) | CYP3A4TSHRCYP2D6CYP2C19LMNA | |
| SCHEMBL2199277 | 0.84 | FAAH (0.47) | CYP3A4TSHRCYP2D6CYP2C19LMNA | |
| SCHEMBL18381376 | 0.84 | FAAH (0.55) | CYP3A4TSHRCPB2SLC7A5FAAH | |
| SCHEMBL2180528 | 0.83 | CYP3A4 (0.49) | CYP3A4TSHRCYP2D6CYP2C19LMNA | |
| SCHEMBL2276192 | 0.82 | QPCT (0.56) | CYP3A4TSHRCYP2D6CYP2C19LMNA | |
| SCHEMBL2177294 | 0.81 | FAAH (0.50) | CYP3A4TSHRCYP2D6CYP2C19LMNA | |
| Carnosine SCHEMBL1160796 | 0.81 | SLC15A2 (0.63) | CYP3A4TSHRCYP2D6CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8623900-B2 | Amino alcohol derivatives and their therapeutic activities | FLAMMA S.P.A. (IT) | 2014-01-07 | — | — | US | claimed |
| EP-2519507-B1 | AMINO ALCOHOL DERIVATIVES AND THEIR THERAPEUTIC ACTIVITIES | FLAMMA SPA (IT) | 2013-10-16 | — | — | EP | claimed |
| US-20120316212-A1 | AMINO ALCOHOL DERIVATIVES AND THEIR THERAPEUTIC ACTIVITIES | UNIVERSITA DEGLI STUDI DI MILANO (IT) | 2012-12-13 | — | — | US | claimed |
| US-8623900-B2 | Amino alcohol derivatives and their therapeutic activities | FLAMMA S.P.A. (IT) | 2014-01-07 | — | — | US | disclosed |
| EP-2519507-B1 | AMINO ALCOHOL DERIVATIVES AND THEIR THERAPEUTIC ACTIVITIES | FLAMMA SPA (IT) | 2013-10-16 | — | — | EP | disclosed |
| US-20120316212-A1 | AMINO ALCOHOL DERIVATIVES AND THEIR THERAPEUTIC ACTIVITIES | UNIVERSITA DEGLI STUDI DI MILANO (IT) | 2012-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316212-A1 | AMINO ALCOHOL DERIVATIVES AND THEIR THERAPEUTIC ACTIVITIES | ADH1A, ADH5, ADH1C | CYP3A4 480/4885TSHR 2352/4885CYP2D6 418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.