Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2178184 | 0.89 | CYP3A4 (0.56) | SLC15A2CYP3A4SLC7A5CPB2CYP2D6 | |
| SCHEMBL2195381 | 0.89 | CYP3A4 (0.56) | SLC15A2CYP3A4SLC7A5CPB2CYP2D6 | |
| SCHEMBL14152015 | 0.89 | CYP3A4 (0.56) | SLC15A2CYP3A4SLC7A5CPB2CYP2D6 | |
| SCHEMBL18381376 | 0.81 | FAAH (0.55) | SLC15A2CYP3A4SLC7A5CPB2TSHR | |
| SCHEMBL2199277 | 0.81 | FAAH (0.47) | CYP3A4SLC7A5CYP2D6TSHRCYP2C19 | |
| SCHEMBL30081493 | 0.80 | SLC15A2 (0.72) | SLC15A2CYP3A4SLC7A5CPB2CYP2C19 | |
| SCHEMBL2197786 | 0.80 | SLC15A2 (0.72) | SLC15A2CYP3A4SLC7A5CPB2CYP2C19 | |
| SCHEMBL2276192 | 0.79 | QPCT (0.56) | CYP3A4SLC7A5CYP2D6TSHRCYP2C19 | |
| SCHEMBL23312951 | 0.79 | SLC15A2 (0.61) | SLC15A2CYP3A4SLC7A5CPB2CYP2D6 | |
| SCHEMBL16628203 | 0.78 | SLC15A2 (0.63) | SLC15A2CYP3A4SLC7A5CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170190691-A1 | NOVEL 5-ACYLSULFANYL-HISTIDINE COMPOUNDS AS PRECURSORS OF THE CORRESPONDING 5-SULFANYLHISTIDINES AND THEIR DISULFIDES | TETRAHEDRON (FR) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190691-A1 | NOVEL 5-ACYLSULFANYL-HISTIDINE COMPOUNDS AS PRECURSORS OF THE CORRESPONDING 5-SULFANYLHISTIDINES AND THEIR DISULFIDES | AHCYL1, CBS, H1-5 | SLC15A2 1782/4885CYP3A4 2019/4885SLC7A5 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.